Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2680536..2680873 Replicon chromosome
Accession NZ_CP097034
Organism Enterococcus faecalis strain AT40b

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag M2913_RS13030 Protein ID WP_002396786.1
Coordinates 2680536..2680679 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2680611..2680873 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2913_RS13010 2675752..2675967 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
M2913_RS13015 2676106..2677098 + 993 WP_002378862.1 biotin--[acetyl-CoA-carboxylase] ligase -
M2913_RS13020 2677265..2677903 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
M2913_RS13025 2678588..2680204 + 1617 WP_002378864.1 phosphatase PAP2/LCP family protein -
M2913_RS13030 2680536..2680679 + 144 WP_002396786.1 putative holin-like toxin Toxin
- 2680611..2680873 - 263 - - Antitoxin
M2913_RS13035 2680874..2685565 - 4692 WP_002378865.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T244518 WP_002396786.1 NZ_CP097034:2680536-2680679 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT244518 NZ_CP097034:c2680873-2680611 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References