Detailed information of TA system TA244496

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2655791..2656189
• Replicon: chromosome
• Accession: NZ_CP097031
• Organism: Enterococcus faecalis strain AT41

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2914_RS12755
• Protein ID: WP_021164545.1
• Coordinates: 2656085..2656189 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2655791..2655945 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2914_RS12735 (2650934)	2650934..2651149	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2914_RS12740 (2651288)	2651288..2652280	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2914_RS12745 (2652544)	2652544..2653182	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
M2914_RS12750 (2653867)	2653867..2655483	+	1617	WP_010778027.1	phosphatase PAP2/LCP family protein	-
- (2655757)	2655757..2655933	-	177	NuclAT_14	-	-
- (2655791)	2655791..2655945	-	155	NuclAT_7	-	Antitoxin
M2914_RS12755 (2656085)	2656085..2656189	+	105	WP_021164545.1	putative holin-like toxin	Toxin
- (2656122)	2656122..2656377	-	256	NuclAT_0	-	-
M2914_RS12760 (2656379)	2656379..2660137	-	3759	WP_116495142.1	WxL domain-containing protein	-
- (2660478)	2660478..2660622	-	145	NuclAT_5	-	-
- (2660480)	2660480..2660622	-	143	NuclAT_15	-	-
M2914_RS12765 (2660733)	2660733..2660876	+	144	WP_002387585.1	putative holin-like toxin	-
- (2660851)	2660851..2661065	-	215	NuclAT_2	-	-
- (2661017)	2661017..2661066	+	50	NuclAT_18	-	-
- (2660808)	2660808..2661067	-	260	NuclAT_13	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T244496 WP_021164545.1 NZ_CP097031:2656085-2656189 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 155 bp

>AT244496 NZ_CP097031:c2655945-2655791 [Enterococcus faecalis]
TTTTTAGGTAAGTGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGTGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Structures

Antitoxin