Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 1512830..1513056 Replicon chromosome
Accession NZ_CP097010
Organism Enterococcus faecalis strain AT48

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag M2921_RS07170 Protein ID WP_219843903.1
Coordinates 1512830..1512940 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 1512851..1513056 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2921_RS07160 1508262..1510520 + 2259 WP_010716808.1 DNA helicase PcrA -
M2921_RS07165 1510646..1512676 + 2031 WP_002398122.1 NAD-dependent DNA ligase LigA -
M2921_RS07170 1512830..1512940 + 111 WP_219843903.1 putative holin-like toxin Toxin
- 1512851..1513056 - 206 - - Antitoxin
M2921_RS07175 1513258..1513563 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
M2921_RS07180 1513563..1515032 + 1470 WP_002398120.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
M2921_RS07185 1515032..1516462 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
M2921_RS07190 1516481..1517569 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-33)


Sequences

Toxin        


Download         Length: 37 a.a.        Molecular weight: 3805.59 Da        Isoelectric Point: 5.9482

>T244412 WP_219843903.1 NZ_CP097010:1512830-1512940 [Enterococcus faecalis]
MSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 111 bp

Antitoxin


Download         Length: 206 bp

>AT244412 NZ_CP097010:c1513056-1512851 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References