Detailed information of TA system TA244403

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 907590..907882
• Replicon: chromosome
• Accession: NZ_CP097010
• Organism: Enterococcus faecalis strain AT48

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2921_RS04225
• Protein ID: WP_021164545.1
• Coordinates: 907590..907694 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	907627..907882 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2921_RS04205	902830..903045	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2921_RS04210	903184..904176	+	993	WP_002398510.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2921_RS04215	904343..904981	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
M2921_RS04220	905665..907281	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
M2921_RS04225	907590..907694	+	105	WP_021164545.1	putative holin-like toxin	Toxin
-	907627..907882	-	256	-	-	Antitoxin
M2921_RS04230	907884..911663	-	3780	WP_010818049.1	WxL domain-containing protein	-
M2921_RS04235	912258..912401	+	144	WP_002396786.1	putative holin-like toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T244403 WP_021164545.1 NZ_CP097010:907590-907694 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 256 bp

>AT244403 NZ_CP097010:c907882-907627 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTGAAATAGGAGGCTCAGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGTGTTAATTATTTAAA
AATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin