Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2622089..2622424 Replicon chromosome
Accession NZ_CP097006
Organism Enterococcus faecalis strain LS05-1

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag M2924_RS12270 Protein ID WP_002415596.1
Coordinates 2622089..2622232 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2622374..2622424 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2924_RS12250 (2617157) 2617157..2617372 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
M2924_RS12255 (2617511) 2617511..2618503 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
M2924_RS12260 (2618807) 2618807..2619445 - 639 WP_002375448.1 lytic polysaccharide monooxygenase -
M2924_RS12265 (2620132) 2620132..2621748 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
M2924_RS12270 (2622089) 2622089..2622232 + 144 WP_002415596.1 type I toxin-antitoxin system toxin PepG1 Toxin
- (2622165) 2622165..2622423 - 259 NuclAT_3 - -
- (2622374) 2622374..2622424 + 51 NuclAT_13 - Antitoxin
M2924_RS12275 (2622425) 2622425..2626192 - 3768 WP_104807327.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5314.46 Da        Isoelectric Point: 10.6323

>T244376 WP_002415596.1 NZ_CP097006:2622089-2622232 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 144 bp

Antitoxin


Download         Length: 51 bp

>AT244376 NZ_CP097006:2622374-2622424 [Enterococcus faecalis]
AATAAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References