Detailed information of TA system TA244374

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2622089..2622423
• Replicon: chromosome
• Accession: NZ_CP097006
• Organism: Enterococcus faecalis strain LS05-1

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2924_RS12270
• Protein ID: WP_002415596.1
• Coordinates: 2622089..2622232 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2622165..2622423 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2924_RS12250 (2617157)	2617157..2617372	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
M2924_RS12255 (2617511)	2617511..2618503	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
M2924_RS12260 (2618807)	2618807..2619445	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
M2924_RS12265 (2620132)	2620132..2621748	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
M2924_RS12270 (2622089)	2622089..2622232	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2622165)	2622165..2622423	-	259	NuclAT_3	-	Antitoxin
- (2622374)	2622374..2622424	+	51	NuclAT_13	-	-
M2924_RS12275 (2622425)	2622425..2626192	-	3768	WP_104807327.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T244374 WP_002415596.1 NZ_CP097006:2622089-2622232 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 259 bp

>AT244374 NZ_CP097006:c2622423-2622165 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAA
TGATAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTACTT
AAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAA
GCAATGGTAAACATACCAA

Structures

Antitoxin