Detailed information of TA system TA244371

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2543644..2543915
• Replicon: chromosome
• Accession: NZ_CP097006
• Organism: Enterococcus faecalis strain LS05-1

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: M2924_RS11925
• Protein ID: WP_002375510.1
• Coordinates: 2543763..2543915 (-)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2543644..2543830 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M2924_RS11910 (2539611)	2539611..2542355	+	2745	WP_104807179.1	glycosyl hydrolase family 65 protein	-
M2924_RS11915 (2542370)	2542370..2543020	+	651	WP_002375514.1	beta-phosphoglucomutase	-
- (2543089)	2543089..2543221	+	133	NuclAT_12	-	-
- (2543268)	2543268..2543455	+	188	NuclAT_4	-	-
M2924_RS11920 (2543388)	2543388..2543492	-	105	WP_023894767.1	putative holin-like toxin	-
- (2543644)	2543644..2543789	+	146	NuclAT_11	-	-
- (2543644)	2543644..2543830	+	187	NuclAT_5	-	Antitoxin
M2924_RS11925 (2543763)	2543763..2543915	-	153	WP_002375510.1	type I toxin-antitoxin system toxin PepG1	Toxin
M2924_RS11930 (2544140)	2544140..2545111	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
M2924_RS11935 (2545286)	2545286..2545723	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
M2924_RS11940 (2545856)	2545856..2546410	-	555	WP_002354869.1	Maf family protein	-
M2924_RS11945 (2546435)	2546435..2548567	-	2133	WP_002375508.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (17-50)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5637.90 Da
• Isoelectric Point: 11.0942

>T244371 WP_002375510.1 NZ_CP097006:c2543915-2543763 [Enterococcus faecalis]
VVRMSALPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 153 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT244371 NZ_CP097006:2543644-2543830 [Enterococcus faecalis]
TGTGCTATAATGAAAATGAAAAGAGAGATATGAGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTTTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin