Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3318112..3318629 Replicon chromosome
Accession NZ_CP096972
Organism Sphingomonas sp. SUN039

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag M0209_RS16470 Protein ID WP_258889362.1
Coordinates 3318112..3318378 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M0209_RS16475 Protein ID WP_258889363.1
Coordinates 3318375..3318629 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0209_RS16445 (M0209_16425) 3313709..3314509 + 801 WP_258889357.1 enoyl-ACP reductase FabI -
M0209_RS16450 (M0209_16430) 3314506..3315570 + 1065 WP_258889358.1 chorismate synthase -
M0209_RS16455 (M0209_16435) 3315570..3316748 + 1179 WP_258889359.1 hypothetical protein -
M0209_RS16460 (M0209_16440) 3316786..3317379 - 594 WP_258889360.1 trimeric intracellular cation channel family protein -
M0209_RS16465 (M0209_16445) 3317376..3318101 - 726 WP_258889361.1 alpha/beta hydrolase -
M0209_RS16470 (M0209_16450) 3318112..3318378 - 267 WP_258889362.1 Txe/YoeB family addiction module toxin Toxin
M0209_RS16475 (M0209_16455) 3318375..3318629 - 255 WP_258889363.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M0209_RS16480 (M0209_16460) 3318680..3319066 - 387 WP_258889364.1 type II toxin-antitoxin system VapC family toxin -
M0209_RS16485 (M0209_16465) 3319063..3319299 - 237 WP_258889365.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
M0209_RS16490 (M0209_16470) 3319481..3321319 - 1839 WP_258889366.1 translational GTPase TypA -
M0209_RS16495 (M0209_16475) 3321399..3321506 - 108 WP_258889367.1 DUF2474 domain-containing protein -
M0209_RS16500 (M0209_16480) 3321490..3322497 - 1008 WP_258889368.1 cytochrome d ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10487.96 Da        Isoelectric Point: 9.5682

>T244304 WP_258889362.1 NZ_CP096972:c3318378-3318112 [Sphingomonas sp. SUN039]
MKIVLSARAWGQYVAWQADDPKTAARINVMIDDIMRSPFRGIGKPEPLRENWRGWWSRRIDDEHRLIYRVTGAGEDQRLE
IAQCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9454.69 Da        Isoelectric Point: 4.5950

>AT244304 WP_258889363.1 NZ_CP096972:c3318629-3318375 [Sphingomonas sp. SUN039]
MIHVSSSDLRKNLAHYMDRAEADRDPILVTRQGSEPVVILAHSEFESMMETLYLRRSPANAAWLDASIAEIEAGNVVEFK
LPQD

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References