Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2674922..2675442 Replicon chromosome
Accession NZ_CP096971
Organism Sphingomonas sp. SUN019

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag M0208_RS12835 Protein ID WP_258892075.1
Coordinates 2675176..2675442 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag M0208_RS12830 Protein ID WP_258892074.1
Coordinates 2674922..2675179 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0208_RS12795 2670331..2670456 + 126 WP_258892067.1 hypothetical protein -
M0208_RS12800 (M0208_12785) 2670501..2670782 + 282 WP_258892068.1 DUF427 domain-containing protein -
M0208_RS12805 (M0208_12790) 2670810..2671529 + 720 WP_258892069.1 DUF6445 family protein -
M0208_RS12810 (M0208_12795) 2671529..2672221 + 693 WP_258892070.1 uracil-DNA glycosylase -
M0208_RS12815 (M0208_12800) 2672261..2672956 + 696 WP_258892071.1 endonuclease III -
M0208_RS12820 (M0208_12805) 2673254..2674072 - 819 WP_258892072.1 hypothetical protein -
M0208_RS12825 (M0208_12810) 2674368..2674745 - 378 WP_258892073.1 VOC family protein -
M0208_RS12830 (M0208_12815) 2674922..2675179 + 258 WP_258892074.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
M0208_RS12835 (M0208_12820) 2675176..2675442 + 267 WP_258892075.1 Txe/YoeB family addiction module toxin Toxin
M0208_RS12840 (M0208_12825) 2675436..2675861 - 426 WP_258892076.1 VOC family protein -
M0208_RS12845 (M0208_12830) 2675940..2677118 + 1179 WP_258892077.1 DUF3644 domain-containing protein -
M0208_RS12850 (M0208_12835) 2677124..2679004 - 1881 WP_258892078.1 phosphomethylpyrimidine synthase ThiC -
M0208_RS12855 (M0208_12840) 2679240..2680256 - 1017 WP_258892079.1 ferritin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10519.92 Da        Isoelectric Point: 8.4981

>T244297 WP_258892075.1 NZ_CP096971:2675176-2675442 [Sphingomonas sp. SUN019]
VKVSFDREAWAEYLQWQREDVRVLENISGLIEECRRDPFRGTGKPEPLKRDLAGWWSRRITGEHRLIYRALRSGDAQVVE
VLSCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9507.80 Da        Isoelectric Point: 4.8783

>AT244297 WP_258892074.1 NZ_CP096971:2674922-2675179 [Sphingomonas sp. SUN019]
MMQTVSYSEARENLKAMIDKVVADRAPITITRQRGEGAVLISESEWAGMEETLHLLSSPANARRLLEGIKRFDAGEGEEH
ELIRP

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References