24420

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2222557..2222773 Replicon chromosome
Accession NC_013450
Organism Staphylococcus aureus subsp. aureus ED98

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAAV_RS11355 Protein ID WP_001802298.1
Coordinates 2222669..2222773 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2222557..2222612 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAAV_RS11335 2218763..2219428 - 666 WP_001024092.1 SDR family oxidoreductase -
SAAV_RS11340 2219580..2219900 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAAV_RS11345 2219902..2220879 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SAAV_RS11350 2221145..2222236 + 1092 WP_000495669.1 hypothetical protein -
- 2222557..2222612 + 56 - - Antitoxin
SAAV_RS11355 2222669..2222773 - 105 WP_001802298.1 hypothetical protein Toxin
SAAV_RS15025 2223453..2223611 + 159 WP_001792784.1 hypothetical protein -
SAAV_RS11360 2224269..2225126 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
SAAV_RS11365 2225194..2225976 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T24420 WP_001802298.1 NC_013450:c2222773-2222669 [Staphylococcus aureus subsp. aureus ED98]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T24420 NC_013450:c2222773-2222669 [Staphylococcus aureus subsp. aureus ED98]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT24420 NC_013450:2222557-2222612 [Staphylococcus aureus subsp. aureus ED98]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References