Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1966931..1967631 Replicon chromosome
Accession NZ_CP096920
Organism Pseudomonas putida strain NY4811

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2I0CDW7
Locus tag M2J85_RS09055 Protein ID WP_003254238.1
Coordinates 1966931..1967227 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag M2J85_RS09060 Protein ID WP_003254235.1
Coordinates 1967230..1967631 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M2J85_RS09035 (M2J85_08995) 1962567..1964192 + 1626 WP_060538696.1 twin-arginine translocation signal domain-containing protein -
M2J85_RS09040 (M2J85_09000) 1964314..1964790 + 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
M2J85_RS09045 (M2J85_09005) 1964959..1965438 + 480 WP_012051716.1 hypothetical protein -
M2J85_RS09050 (M2J85_09010) 1965511..1966836 + 1326 WP_047604115.1 MFS transporter -
M2J85_RS09055 (M2J85_09015) 1966931..1967227 + 297 WP_003254238.1 type II toxin-antitoxin system MqsR family toxin Toxin
M2J85_RS09060 (M2J85_09020) 1967230..1967631 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
M2J85_RS09065 (M2J85_09025) 1967703..1969385 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
M2J85_RS09070 (M2J85_09030) 1969921..1970670 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
M2J85_RS09075 (M2J85_09035) 1970671..1971600 + 930 WP_003254230.1 FAD-binding protein -
M2J85_RS09080 (M2J85_09040) 1971676..1972497 + 822 WP_003254229.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11110.18 Da        Isoelectric Point: 10.2270

>T244172 WP_003254238.1 NZ_CP096920:1966931-1967227 [Pseudomonas putida]
MEKRMPNCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT244172 WP_003254235.1 NZ_CP096920:1967230-1967631 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I0CDW7

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References