Detailed information of TA system TA243487

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 2636126..2636346
• Replicon: chromosome
• Accession: NZ_CP096837
• Organism: Escherichia coli strain PS10-3

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: J7R083
• Locus tag: MYF74_RS12430
• Protein ID: WP_000170963.1
• Coordinates: 2636239..2636346 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	2636126..2636192 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MYF74_RS12405	2631404..2632798	-	1395	WP_000086192.1	inverse autotransporter invasin YchO	-
MYF74_RS12410	2632984..2633337	+	354	WP_001169669.1	DsrE/F sulfur relay family protein YchN	-
MYF74_RS12415	2633381..2634076	-	696	WP_001307738.1	glutathione-specific gamma-glutamylcyclotransferase	-
MYF74_RS12420	2634234..2634464	-	231	WP_001146444.1	putative cation transport regulator ChaB	-
MYF74_RS12425	2634734..2635834	+	1101	WP_000063607.1	sodium-potassium/proton antiporter ChaA	-
-	2636126..2636192	-	67	-	-	Antitoxin
MYF74_RS12430	2636239..2636346	+	108	WP_000170963.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
MYF74_RS12435	2636495..2637349	-	855	WP_000811055.1	3-deoxy-8-phosphooctulonate synthase	-
MYF74_RS12440	2637385..2638194	-	810	WP_001257044.1	invasion regulator SirB1	-
MYF74_RS12445	2638198..2638590	-	393	WP_044191662.1	invasion regulator SirB2	-
MYF74_RS12450	2638587..2639420	-	834	WP_000456466.1	peptide chain release factor N(5)-glutamine methyltransferase	-
MYF74_RS12455	2639420..2640502	-	1083	WP_000804726.1	peptide chain release factor 1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3971.74 Da
• Isoelectric Point: 11.4779

>T243487 WP_000170963.1 NZ_CP096837:2636239-2636346 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Nucleotide

• Length: 108 bp

>T243487 NZ_OX352831:c1955181-1954924 [Streptococcus suis]
ATGGGAATCCATTTTACAGACGACGCCTGGGAAGACTATCTTTATTGGCAGGGTCAGGATAAGAAAACACTGAAGAGAAT
CAATAAGATTATCCAGGATATGCAGCGACATCCTTTTGAAGGCATTGCCAAACCAGAACCTTTGAAGTATGATTATCAAG
GTGCCTGGTCTCGGAGAATTGATGCGGAGAATCGGTTGATTTATATGGTGGAAGCTGATCGGTTGTGCATCCTGTCGCTA
AAGGATCATTATAGGTGA

Antitoxin

Nucleotide

• Length: 67 bp

>AT243487 NZ_CP096837:c2636192-2636126 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Structures

Antitoxin