Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2486971..2487155 Replicon chromosome
Accession NZ_CP096522
Organism Staphylococcus aureus strain RIVM_M085090

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag M1F52_RS12280 Protein ID WP_000482647.1
Coordinates 2487048..2487155 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2486971..2487031 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1F52_RS12265 (M1F52_12245) 2482425..2482592 - 168 WP_001798790.1 hypothetical protein -
M1F52_RS12270 (M1F52_12250) 2482823..2484556 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
M1F52_RS12275 (M1F52_12255) 2484581..2486344 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2486971..2487031 + 61 - - Antitoxin
M1F52_RS12280 (M1F52_12260) 2487048..2487155 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
M1F52_RS12285 (M1F52_12265) 2487289..2487675 - 387 WP_000779355.1 flippase GtxA -
M1F52_RS12290 (M1F52_12270) 2487942..2489084 + 1143 WP_001176859.1 glycerate kinase -
M1F52_RS12295 (M1F52_12275) 2489144..2489803 + 660 WP_000831300.1 hypothetical protein -
M1F52_RS12300 (M1F52_12280) 2489991..2491202 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
M1F52_RS12305 (M1F52_12285) 2491325..2491798 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T243080 WP_000482647.1 NZ_CP096522:c2487155-2487048 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T243080 NZ_CP096522:c2487155-2487048 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT243080 NZ_CP096522:2486971-2487031 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References