Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2656321..2656584 Replicon chromosome
Accession NZ_CP096272
Organism Staphylococcus aureus strain FJ0318

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag M1E49_RS13105 Protein ID WP_001802298.1
Coordinates 2656321..2656425 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2656420..2656584 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M1E49_RS13080 2651705..2652487 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
M1E49_RS13085 2652555..2653412 + 858 WP_000370924.1 HAD family hydrolase -
M1E49_RS13090 2654117..2654209 - 93 WP_001790138.1 hypothetical protein -
M1E49_RS13095 2654498..2655634 + 1137 WP_000115564.1 SAP domain-containing protein -
M1E49_RS13100 2655677..2656160 + 484 Protein_2542 recombinase family protein -
M1E49_RS13105 2656321..2656425 + 105 WP_001802298.1 hypothetical protein Toxin
- 2656420..2656584 - 165 - - Antitoxin
M1E49_RS13115 2656868..2657959 - 1092 WP_000495683.1 hypothetical protein -
M1E49_RS13120 2658225..2659205 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
M1E49_RS13125 2659207..2659527 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
M1E49_RS13130 2659679..2660344 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T243044 WP_001802298.1 NZ_CP096272:2656321-2656425 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T243044 NZ_OW968417:c2713822-2713719 [Enterobacter cloacae]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 165 bp

>AT243044 NZ_CP096272:c2656584-2656420 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References