Detailed information of TA system TA242739

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1871647..1871827
• Replicon: chromosome
• Accession: NZ_CP096114
• Organism: Staphylococcus argenteus strain MRSA-139-14-168

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: M0D62_RS08900
• Protein ID: WP_142290098.1
• Coordinates: 1871647..1871742 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1871770..1871827 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
M0D62_RS08865 (M0D62_08855)	1866680..1867300	+	621	WP_047435175.1	hypothetical protein	-
M0D62_RS08870 (M0D62_08860)	1867341..1867682	+	342	WP_047435178.1	DUF3969 family protein	-
M0D62_RS08875 (M0D62_08865)	1867783..1868355	+	573	WP_047435181.1	hypothetical protein	-
M0D62_RS08880 (M0D62_08870)	1868715..1869542	+	828	WP_047435184.1	ABC transporter ATP-binding protein	-
M0D62_RS08885 (M0D62_08875)	1870360..1870803	-	444	WP_047435190.1	DUF1433 domain-containing protein	-
M0D62_RS13585 (M0D62_08880)	1870954..1871196	-	243	WP_047435192.1	IS3 family transposase	-
M0D62_RS08895 (M0D62_08885)	1871238..1871519	-	282	WP_000196444.1	IS3 family transposase	-
M0D62_RS08900 (M0D62_08890)	1871647..1871742	+	96	WP_142290098.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1871770..1871827	-	58	-	-	Antitoxin
M0D62_RS08905 (M0D62_08895)	1871865..1871966	+	102	WP_047435268.1	hypothetical protein	-
M0D62_RS08910 (M0D62_08900)	1871944..1872120	-	177	Protein_1721	transposase	-
M0D62_RS08915 (M0D62_08905)	1872290..1872733	-	444	WP_047435196.1	DUF1433 domain-containing protein	-
M0D62_RS08920 (M0D62_08910)	1872733..1873176	-	444	WP_047435198.1	DUF1433 domain-containing protein	-
M0D62_RS08925 (M0D62_08915)	1873176..1873622	-	447	WP_088811285.1	DUF1433 domain-containing protein	-
M0D62_RS08930 (M0D62_08920)	1873622..1874068	-	447	WP_047435204.1	DUF1433 domain-containing protein	-
M0D62_RS08935 (M0D62_08925)	1874068..1874511	-	444	WP_047435208.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1871238..1871519	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3582.37 Da
• Isoelectric Point: 10.4449

>T242739 WP_142290098.1 NZ_CP096114:1871647-1871742 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCVIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T242739 NZ_OW967007:6809-7069 [Escherichia coli]
ATGAAAATAAGAAAAGGTGACAGACAATATTATCTGAATAAAGAAGGTGATACGTTTCATCTGGTGAAGCGAGTAAAAAC
TTTTTCTAAGTCTGCGACTTTAGGAAAAACGAAAGCAACGGTGAAAACTGTTGCTGATCTTGTTTTTCATGAGAAGGCAT
TCGACACTATCGACTTTGCCAGCGACGGATTAAGAGAGAATGATAAAGAAATTGTTTTTATGATGATTCAGGAAATGAGC
GAGGGAAAAAATGCTAAATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT242739 NZ_CP096114:c1871827-1871770 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin