Detailed information of TA system TA242735

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 53964..54196
• Replicon: plasmid pW208
• Accession: NZ_CP096049
• Organism: Enterococcus faecalis strain AKSZ-208

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: MZO28_RS00345
• Protein ID: WP_002387930.1
• Coordinates: 53964..54065 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	54105..54196 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZO28_RS00305 (49233)	49233..49457	-	225	WP_002395938.1	ultraviolet resistance protein UvrA repressor UvrC	-
MZO28_RS00310 (49451)	49451..49765	-	315	WP_010774426.1	hypothetical protein	-
MZO28_RS00315 (49755)	49755..50375	-	621	WP_029656234.1	recombinase family protein	-
MZO28_RS00320 (50554)	50554..51237	+	684	Protein_63	IS6-like element IS1216 family transposase	-
MZO28_RS00325 (51301)	51301..51603	+	303	WP_113795156.1	DUF6440 family protein	-
MZO28_RS00330 (52029)	52029..53357	+	1329	WP_033919362.1	ultraviolet resistance protein UvrA	-
MZO28_RS00335 (53354)	53354..53704	+	351	WP_010713025.1	hypothetical protein	-
MZO28_RS00340 (53661)	53661..53873	+	213	WP_002395323.1	hypothetical protein	-
MZO28_RS00345 (53964)	53964..54065	+	102	WP_002387930.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (54105)	54105..54196	-	92	NuclAT_0	-	Antitoxin
- (54105)	54105..54196	-	92	NuclAT_0	-	Antitoxin
- (54105)	54105..54196	-	92	NuclAT_0	-	Antitoxin
- (54105)	54105..54196	-	92	NuclAT_0	-	Antitoxin
MZO28_RS00350 (54306)	54306..54602	+	297	WP_113795155.1	type III secretion system protein PrgN	-
MZO28_RS00355 (54856)	54856..55638	+	783	WP_002369746.1	ParA family protein	-
MZO28_RS00360 (55631)	55631..55987	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	erm(B) / fexA / optrA / aac(6')-aph(2'')	-	1..56246	56246

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3731.42 Da
• Isoelectric Point: 4.1672

>T242735 WP_002387930.1 NZ_CP096049:53964-54065 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 102 bp

>T242735 NZ_OW967003:c4172590-4172213 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGACACTACTGTC
CCGACTGCTGGACCAGCACTACGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGAATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTATCCTGGGTAAGCACCCGGAGGTGAAACAATGA

Antitoxin

Nucleotide

• Length: 92 bp

>AT242735 NZ_CP096049:c54196-54105 [Enterococcus faecalis]
TAAAAATATGTTATACTATAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin