Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/Fst(toxin)
Location 53964..54169 Replicon plasmid pW208
Accession NZ_CP096049
Organism Enterococcus faecalis strain AKSZ-208

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag MZO28_RS00345 Protein ID WP_002387930.1
Coordinates 53964..54065 (+) Length 34 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 54105..54169 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZO28_RS00305 49233..49457 - 225 WP_002395938.1 ultraviolet resistance protein UvrA repressor UvrC -
MZO28_RS00310 49451..49765 - 315 WP_010774426.1 hypothetical protein -
MZO28_RS00315 49755..50375 - 621 WP_029656234.1 recombinase family protein -
MZO28_RS00320 50554..51237 + 684 Protein_63 IS6-like element IS1216 family transposase -
MZO28_RS00325 51301..51603 + 303 WP_113795156.1 DUF6440 family protein -
MZO28_RS00330 52029..53357 + 1329 WP_033919362.1 ultraviolet resistance protein UvrA -
MZO28_RS00335 53354..53704 + 351 WP_010713025.1 hypothetical protein -
MZO28_RS00340 53661..53873 + 213 WP_002395323.1 hypothetical protein -
MZO28_RS00345 53964..54065 + 102 WP_002387930.1 type I toxin-antitoxin system Fst family toxin Toxin
- 54105..54169 - 65 - - Antitoxin
MZO28_RS00350 54306..54602 + 297 WP_113795155.1 type III secretion system protein PrgN -
MZO28_RS00355 54856..55638 + 783 WP_002369746.1 ParA family protein -
MZO28_RS00360 55631..55987 + 357 WP_002360663.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid erm(B) / fexA / optrA / aac(6')-aph(2'') - 1..56246 56246


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 34 a.a.        Molecular weight: 3731.42 Da        Isoelectric Point: 4.1672

>T242732 WP_002387930.1 NZ_CP096049:53964-54065 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Download         Length: 102 bp

>T242732 NZ_OW967003:3410609-3410794 [Escherichia coli]
GTGAAAAGTGCAGACGTGATCGCCATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
CCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 65 bp

>AT242732 NZ_CP096049:c54169-54105 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References