Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 858392..859044 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MY525_RS03780 Protein ID WP_250658630.1
Coordinates 858700..859044 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MY525_RS03775 Protein ID WP_250658629.1
Coordinates 858392..858703 (-) Length 104 a.a.

Genomic Context

MY525_RS03760MY525_RS03765MY525_RS03770MY525_RS03775MY525_RS03780MY525_RS03785MY525_RS03790MY525_RS03795MY525_RS03800MY525_RS03805
Location: 854199..855314 (1116 bp)
Type: Others
Protein ID: WP_250658626.1
Location: 855374..856111 (738 bp)
Type: Others
Protein ID: WP_250658627.1
Location: 856348..858342 (1995 bp)
Type: Others
Protein ID: WP_250658628.1
Location: 858392..858703 (312 bp)
Type: Antitoxin
Protein ID: WP_250658629.1
Location: 858700..859044 (345 bp)
Type: Toxin
Protein ID: WP_250658630.1
Location: 859112..859723 (612 bp)
Type: Others
Protein ID: WP_250658631.1
Location: 859836..860516 (681 bp)
Type: Others
Protein ID: WP_250658632.1
Location: 860523..861497 (975 bp)
Type: Others
Protein ID: WP_250658633.1
Location: 861563..862267 (705 bp)
Type: Others
Protein ID: WP_250658634.1
Location: 862285..862638 (354 bp)
Type: Others
Protein ID: WP_250658635.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MY525_RS03760854199..855314+1116WP_250658626.1DegT/DnrJ/EryC1/StrS family aminotransferase-
MY525_RS03765855374..856111+738WP_250658627.1class I SAM-dependent methyltransferase-
MY525_RS03770856348..858342+1995WP_250658628.1hypothetical protein-
MY525_RS03775858392..858703-312WP_250658629.1transcriptional regulatorAntitoxin
MY525_RS03780858700..859044-345WP_250658630.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MY525_RS03785859112..859723-612WP_250658631.1TIGR04282 family arsenosugar biosynthesis glycosyltransferase-
MY525_RS03790859836..860516-681WP_250658632.1TIGR04283 family arsenosugar biosynthesis glycosyltransferase-
MY525_RS03795860523..861497-975WP_250658633.1arsenosugar biosynthesis radical SAM protein ArsS-
MY525_RS03800861563..862267-705WP_250658634.1DsbA family protein-
MY525_RS03805862285..862638-354WP_250658635.1rhodanese-like domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.74 Da        Isoelectric Point: 10.2015

>T242711 WP_250658630.1 NZ_CP096018:c859044-858700 [Alkalimarinus coralli]
MKAVFIELPPFERNRGHYLDDNAYRNFQNEILKNPTSGDLIKGTCGLRKVRYKDERRRKGKRGGVRVIYYWWKEGSQFWL
FTIYDKDEVTDLTKAELKLLADLLKLEIKARSLL

Download         Length: 345 bp

>T242711 NZ_OW849527:4045938-4046279 [Citrobacter freundii]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATAGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGTAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11985.76 Da        Isoelectric Point: 7.2061

>AT242711 WP_250658629.1 NZ_CP096018:c858703-858392 [Alkalimarinus coralli]
MKRNLFEELSEGFQSLKDDREGKTTLKQHLVMATETPEVTSEELISLRERLHLSQAVFADFLRINKRTLENWEQGRVKPN
SQAALLIKMVEKYPDTIQRLGTI

Download         Length: 312 bp

>AT242711 NZ_OW849527:4045600-4045917 [Citrobacter freundii]
ATGAGCAAAATCACATGGGGTCTGCAGCGTGATATCACGCCACGTCTGGGAGCCCGTCTGGTGCAGGAAGGCAACCGACT
GCATTATCTGGCTGACCGGGCCAGCATGACCGGCAAGTTCAGTGACATCGAATACCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCGCCAGATGGAATCGATGCTGACCACTGGTGAACTCAGCACCCACCATGCCCACTGCGTTACCCTGTACCAC
AACGATTTAACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTATACATCGCCATTTACCCCACTCAGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References