Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 858392..859044 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MY525_RS03780 Protein ID WP_250658630.1
Coordinates 858700..859044 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MY525_RS03775 Protein ID WP_250658629.1
Coordinates 858392..858703 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY525_RS03760 854199..855314 + 1116 WP_250658626.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
MY525_RS03765 855374..856111 + 738 WP_250658627.1 class I SAM-dependent methyltransferase -
MY525_RS03770 856348..858342 + 1995 WP_250658628.1 hypothetical protein -
MY525_RS03775 858392..858703 - 312 WP_250658629.1 transcriptional regulator Antitoxin
MY525_RS03780 858700..859044 - 345 WP_250658630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY525_RS03785 859112..859723 - 612 WP_250658631.1 TIGR04282 family arsenosugar biosynthesis glycosyltransferase -
MY525_RS03790 859836..860516 - 681 WP_250658632.1 TIGR04283 family arsenosugar biosynthesis glycosyltransferase -
MY525_RS03795 860523..861497 - 975 WP_250658633.1 arsenosugar biosynthesis radical SAM protein ArsS -
MY525_RS03800 861563..862267 - 705 WP_250658634.1 DsbA family protein -
MY525_RS03805 862285..862638 - 354 WP_250658635.1 rhodanese-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.74 Da        Isoelectric Point: 10.2015

>T242711 WP_250658630.1 NZ_CP096018:c859044-858700 [Alkalimarinus coralli]
MKAVFIELPPFERNRGHYLDDNAYRNFQNEILKNPTSGDLIKGTCGLRKVRYKDERRRKGKRGGVRVIYYWWKEGSQFWL
FTIYDKDEVTDLTKAELKLLADLLKLEIKARSLL

Download         Length: 345 bp

>T242711 NZ_OW849527:4045938-4046279 [Citrobacter freundii]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATAGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGTAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11985.76 Da        Isoelectric Point: 7.2061

>AT242711 WP_250658629.1 NZ_CP096018:c858703-858392 [Alkalimarinus coralli]
MKRNLFEELSEGFQSLKDDREGKTTLKQHLVMATETPEVTSEELISLRERLHLSQAVFADFLRINKRTLENWEQGRVKPN
SQAALLIKMVEKYPDTIQRLGTI

Download         Length: 312 bp

>AT242711 NZ_OW849527:4045600-4045917 [Citrobacter freundii]
ATGAGCAAAATCACATGGGGTCTGCAGCGTGATATCACGCCACGTCTGGGAGCCCGTCTGGTGCAGGAAGGCAACCGACT
GCATTATCTGGCTGACCGGGCCAGCATGACCGGCAAGTTCAGTGACATCGAATACCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCGCCAGATGGAATCGATGCTGACCACTGGTGAACTCAGCACCCACCATGCCCACTGCGTTACCCTGTACCAC
AACGATTTAACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTATACATCGCCATTTACCCCACTCAGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References