Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 858092..858744 Replicon chromosome
Accession NZ_CP096017
Organism Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MY524_RS03775 Protein ID WP_250658630.1
Coordinates 858400..858744 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MY524_RS03770 Protein ID WP_250658629.1
Coordinates 858092..858403 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY524_RS03755 853899..855014 + 1116 WP_250658626.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
MY524_RS03760 855074..855811 + 738 WP_250658627.1 class I SAM-dependent methyltransferase -
MY524_RS03765 856048..858042 + 1995 WP_250658628.1 hypothetical protein -
MY524_RS03770 858092..858403 - 312 WP_250658629.1 transcriptional regulator Antitoxin
MY524_RS03775 858400..858744 - 345 WP_250658630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY524_RS03780 858812..859423 - 612 WP_250658631.1 TIGR04282 family arsenosugar biosynthesis glycosyltransferase -
MY524_RS03785 859536..860216 - 681 WP_250658632.1 TIGR04283 family arsenosugar biosynthesis glycosyltransferase -
MY524_RS03790 860223..861197 - 975 WP_250658633.1 arsenosugar biosynthesis radical SAM protein ArsS -
MY524_RS03795 861263..861967 - 705 WP_250658634.1 DsbA family protein -
MY524_RS03800 861985..862338 - 354 WP_250658635.1 rhodanese-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.74 Da        Isoelectric Point: 10.2015

>T242700 WP_250658630.1 NZ_CP096017:c858744-858400 [Alkalimarinus coralli]
MKAVFIELPPFERNRGHYLDDNAYRNFQNEILKNPTSGDLIKGTCGLRKVRYKDERRRKGKRGGVRVIYYWWKEGSQFWL
FTIYDKDEVTDLTKAELKLLADLLKLEIKARSLL

Download         Length: 345 bp

>T242700 NZ_OW849470:4370682-4370900 [Klebsiella oxytoca]
ATGTCTGATAAAACATTAACCAAAATAGACTATTTGATGCGCTTACGACGTTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAAAATAAATATGAACTTTCTGATAATGAACTGGCGGTATTTTACTCAGCAGCCGATCATCGTCTTGCTGAAC
TGACGATGAATAAACTGTATGACAAGATCCCGCCATCGGTCTGGAAATTCATCCGCTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11985.76 Da        Isoelectric Point: 7.2061

>AT242700 WP_250658629.1 NZ_CP096017:c858403-858092 [Alkalimarinus coralli]
MKRNLFEELSEGFQSLKDDREGKTTLKQHLVMATETPEVTSEELISLRERLHLSQAVFADFLRINKRTLENWEQGRVKPN
SQAALLIKMVEKYPDTIQRLGTI

Download         Length: 312 bp

>AT242700 NZ_OW849470:4370281-4370655 [Klebsiella oxytoca]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTTAATGACCCAACCTCTGCTGTCAATCTTCAGCTTAATGAATTGATCGAGC
ACATTGCCGCGTTCGCACTTAATTATAAAATTAAGTATGCTGAGGATAATAAGCTGGTGACTCAGCTTGACGAATATCTG
GATGACACTTTCGTGTTGTTCAGCAACTACGGCATTAACACTGCAGATCTGCAGAAATGGCGTAAATCAGGCAACAGGTT
ATTCCGCTGCTTTGTGAACGCCAGTCGGGAAAACCCGGCCAGTCTTTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References