242690

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2272906..2273558 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MY523_RS10035 Protein ID WP_250658630.1
Coordinates 2273214..2273558 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MY523_RS10030 Protein ID WP_250658629.1
Coordinates 2272906..2273217 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS10015 2268713..2269828 + 1116 WP_250658626.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
MY523_RS10020 2269888..2270625 + 738 WP_250658627.1 class I SAM-dependent methyltransferase -
MY523_RS10025 2270862..2272856 + 1995 WP_250658628.1 hypothetical protein -
MY523_RS10030 2272906..2273217 - 312 WP_250658629.1 transcriptional regulator Antitoxin
MY523_RS10035 2273214..2273558 - 345 WP_250658630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY523_RS10040 2273626..2274237 - 612 WP_250658631.1 TIGR04282 family arsenosugar biosynthesis glycosyltransferase -
MY523_RS10045 2274350..2275030 - 681 WP_250658632.1 TIGR04283 family arsenosugar biosynthesis glycosyltransferase -
MY523_RS10050 2275037..2276011 - 975 WP_250658633.1 arsenosugar biosynthesis radical SAM protein ArsS -
MY523_RS10055 2276077..2276781 - 705 WP_250658634.1 DsbA family protein -
MY523_RS10060 2276799..2277152 - 354 WP_250658635.1 rhodanese-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.74 Da        Isoelectric Point: 10.2015

>T242690 WP_250658630.1 NZ_CP096016:c2273558-2273214 [Alkalimarinus coralli]
MKAVFIELPPFERNRGHYLDDNAYRNFQNEILKNPTSGDLIKGTCGLRKVRYKDERRRKGKRGGVRVIYYWWKEGSQFWL
FTIYDKDEVTDLTKAELKLLADLLKLEIKARSLL

Download         Length: 345 bp

>T242690 NZ_OW849377:c4115848-4115477 [Escherichia coli]
ATGCAAACTATATCATCACACCCGACACGGGCGACTCAGCCCTGCCTGTCACCCGTTGAAATCTGGCAGCGGTTACTGAC
TTGTCTGTTGTCGCAGCACTATGGTCTGACGTTGAATGACACACCGTTCAGTAATGAAACCACCATACTGGAACACATTG
ATGCTGGAGTATCGCTGTGCGATGCGGTGAACTTTCTTGTTGAAAAATATGAACTGGTAAGAATTGACTGTAATGATTGC
TCTGTCATGGAGAAGTCACCGTTCATCACCAGTATCGATATTCTACGTGCCCGGAAAGCCTCCGGTCTGATGAAACGCAA
CAGTCACAAAACTGTTACCAGGGTAACGGCAGGTCGACTTCAGGAGCTATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11985.76 Da        Isoelectric Point: 7.2061

>AT242690 WP_250658629.1 NZ_CP096016:c2273217-2272906 [Alkalimarinus coralli]
MKRNLFEELSEGFQSLKDDREGKTTLKQHLVMATETPEVTSEELISLRERLHLSQAVFADFLRINKRTLENWEQGRVKPN
SQAALLIKMVEKYPDTIQRLGTI

Download         Length: 312 bp

>AT242690 NZ_OW849377:c4116252-4115887 [Escherichia coli]
ATGAACAATCACTCAGAATCCGGTACAAAGCCGGAGAATCCCGCCTGCCAGCAGTGGGGGCTTAAATGTGCTATTACCCC
CTGTTTTGGTGCCCGCCTGGTACAGGAGGGCAACCGATTGCATTTTCTCTCTGACCGCGCAGGATTTAGCGGGGCATTTG
CCGTCGATGTTGCAATGCGCCTTGACCAGGCATTTCCGTTAATGATGAAGCAACTTGAGCTGATGCTGACCAGTGGAGAG
CTTAACCCTCGCCACCCACACTGCGTCACGCTTTACCACAATGGACTCACCTGTGAAGCCGATACACTAGGCTCCTGTGG
TTATGTCTACATTGCTATCTATCCTGAGCAAACTGAGCCGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References