Detailed information of TA system TA242449

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 2820837..2821537
• Replicon: chromosome
• Accession: NZ_CP095740
• Organism: Luteibacter aegosomatis strain 321

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: L2Y94_RS12595
• Protein ID: WP_247366983.1
• Coordinates: 2821241..2821537 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: L2Y94_RS12590
• Protein ID: WP_247366982.1
• Coordinates: 2820837..2821238 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2Y94_RS12575 (L2Y94_12575)	2816087..2819221	+	3135	WP_247366975.1	CusA/CzcA family heavy metal efflux RND transporter	-
L2Y94_RS12585 (L2Y94_12585)	2819394..2820164	-	771	WP_247366980.1	alpha/beta hydrolase	-
L2Y94_RS12590 (L2Y94_12590)	2820837..2821238	-	402	WP_247366982.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
L2Y94_RS12595 (L2Y94_12595)	2821241..2821537	-	297	WP_247366983.1	type II toxin-antitoxin system MqsR family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Antitoxin MqsA (3-131)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10985.65 Da
• Isoelectric Point: 7.4644

>T242449 WP_247366983.1 NZ_CP095740:c2821537-2821241 [Luteibacter aegosomatis]
VEKGTPHHKLSVVRAWVEAGRVRATYSATRGASHLGLEMSGMLDVLMALSSTDFYKSMTTYADHTLWHDVYRVGTRVGDV
YLKLTIIDEVVIVSFKEL

Nucleotide

• Length: 297 bp

>T242449 NZ_OW443151:319567-319854 [Vibrio cholerae]
ATGACCTATAAGTTAAAGTTTCTGCCGGCTGTGCAAAAGGAATGGAGTAAGTTAGCTCCGACAATTCAGAGTCAGTTCAA
GAAGAAGTTAAAGGAACGATTAGAAAATCCGCACGTCCCTTCGGCTAAGCTTCGAGGATACGACGCTGTTTACAAGATTA
AACTTCGTACGGCGGGTTATCGTTTAGCTTATGAGGTTATTGACGATGAGATAGTTGTCTATGTCCTTGCTGTCGGCAAA
CGTGACAAAGATGCTGTCTATAAAAAACTAGCTTCACGCTTTGGTTAG

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14724.04 Da
• Isoelectric Point: 7.0833

>AT242449 WP_247366982.1 NZ_CP095740:c2821238-2820837 [Luteibacter aegosomatis]
MKCPACGAAELIRDSRDMPYTYKGETTVIPSVAGQFCPTCGEAVLDMGESIRTSELMMQFNKQVNAAIVDPQFIASVRKK
LHLDQREAAEIFGGGVNAFSRYENGKTRPPLALVKLLRLLDRHPDLLDEVRLA

Nucleotide

• Length: 402 bp

>AT242449 NZ_OW443151:319326-319577 [Vibrio cholerae]
ATGAGACAAGTGTTAGCGAATTGCTCTGCAAGTATTTCAGAGTTAAAGAAGAACCCAACGGCTTTGTTGAATGAGGCTGA
TGGGGCTGCAATTGCAATTTTAAACCACAACAAGCCAGCGGCTTACCTTGTGCCAGCGGAAACGTATGAGTATCTCATCG
ATATGCTCGATGATTATGAGCTTTCCCAAATTGTCGATAGTCGCCGAGCGGACTTATCACAAGCTGTGGAAGTAAATATT
GATGACCTATAA