Detailed information of TA system TA242180

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 1953099..1953321
• Replicon: chromosome
• Accession: NZ_CP095518
• Organism: Escherichia coli strain GN02350

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A0D6GD35
• Locus tag: MW405_RS09125
• Protein ID: WP_000170745.1
• Coordinates: 1953099..1953206 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	1953263..1953321 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MW405_RS09100	1948352..1949104	-	753	WP_000279525.1	cellulose biosynthesis protein BcsQ	-
MW405_RS09105	1949116..1949304	-	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-
MW405_RS09110	1949577..1951148	+	1572	WP_001204945.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
MW405_RS09115	1951145..1951336	+	192	WP_000988311.1	cellulose biosynthesis protein BcsF	-
MW405_RS09120	1951333..1953012	+	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
MW405_RS09125	1953099..1953206	-	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	1953263..1953321	+	59	-	-	Antitoxin
MW405_RS09130	1953682..1954953	+	1272	WP_001467807.1	amino acid permease	-
MW405_RS09135	1954983..1955987	-	1005	WP_000103583.1	dipeptide ABC transporter ATP-binding subunit DppF	-
MW405_RS09140	1955984..1956967	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
MW405_RS09145	1956978..1957880	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3855.68 Da
• Isoelectric Point: 9.0157

>T242180 WP_000170745.1 NZ_CP095518:c1953206-1953099 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Nucleotide

• Length: 108 bp

>T242180 NZ_CP095518:c1953206-1953099 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT242180 NZ_CP095518:1953263-1953321 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A0D6GD35

Antitoxin