Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4780557..4780778 Replicon chromosome
Accession NZ_CP095505
Organism Escherichia coli strain GN02050

Toxin (Protein)


Gene name ldrD Uniprot ID J7R083
Locus tag MW398_RS24285 Protein ID WP_000170963.1
Coordinates 4780557..4780664 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4780712..4780778 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW398_RS24260 (4776401) 4776401..4777483 + 1083 WP_000804726.1 peptide chain release factor 1 -
MW398_RS24265 (4777483) 4777483..4778316 + 834 WP_000456474.1 peptide chain release factor N(5)-glutamine methyltransferase -
MW398_RS24270 (4778313) 4778313..4778705 + 393 WP_000200375.1 invasion regulator SirB2 -
MW398_RS24275 (4778709) 4778709..4779518 + 810 WP_001257054.1 invasion regulator SirB1 -
MW398_RS24280 (4779554) 4779554..4780408 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
MW398_RS24285 (4780557) 4780557..4780664 - 108 WP_000170963.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (4780714) 4780714..4780777 + 64 NuclAT_12 - -
- (4780714) 4780714..4780777 + 64 NuclAT_12 - -
- (4780714) 4780714..4780777 + 64 NuclAT_12 - -
- (4780714) 4780714..4780777 + 64 NuclAT_12 - -
- (4780714) 4780714..4780777 + 64 NuclAT_13 - -
- (4780714) 4780714..4780777 + 64 NuclAT_13 - -
- (4780714) 4780714..4780777 + 64 NuclAT_13 - -
- (4780714) 4780714..4780777 + 64 NuclAT_13 - -
- (4780714) 4780714..4780777 + 64 NuclAT_14 - -
- (4780714) 4780714..4780777 + 64 NuclAT_14 - -
- (4780714) 4780714..4780777 + 64 NuclAT_14 - -
- (4780714) 4780714..4780777 + 64 NuclAT_14 - -
- (4780714) 4780714..4780777 + 64 NuclAT_15 - -
- (4780714) 4780714..4780777 + 64 NuclAT_15 - -
- (4780714) 4780714..4780777 + 64 NuclAT_15 - -
- (4780714) 4780714..4780777 + 64 NuclAT_15 - -
- (4780714) 4780714..4780777 + 64 NuclAT_16 - -
- (4780714) 4780714..4780777 + 64 NuclAT_16 - -
- (4780714) 4780714..4780777 + 64 NuclAT_16 - -
- (4780714) 4780714..4780777 + 64 NuclAT_16 - -
- (4780714) 4780714..4780777 + 64 NuclAT_17 - -
- (4780714) 4780714..4780777 + 64 NuclAT_17 - -
- (4780714) 4780714..4780777 + 64 NuclAT_17 - -
- (4780714) 4780714..4780777 + 64 NuclAT_17 - -
- (4780712) 4780712..4780778 + 67 NuclAT_10 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_10 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_10 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_10 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_11 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_11 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_11 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_11 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_6 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_6 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_6 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_6 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_7 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_7 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_7 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_7 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_8 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_8 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_8 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_8 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_9 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_9 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_9 - Antitoxin
- (4780712) 4780712..4780778 + 67 NuclAT_9 - Antitoxin
- (4780714) 4780714..4780779 + 66 NuclAT_19 - -
- (4780714) 4780714..4780779 + 66 NuclAT_19 - -
- (4780714) 4780714..4780779 + 66 NuclAT_19 - -
- (4780714) 4780714..4780779 + 66 NuclAT_19 - -
- (4780714) 4780714..4780779 + 66 NuclAT_20 - -
- (4780714) 4780714..4780779 + 66 NuclAT_20 - -
- (4780714) 4780714..4780779 + 66 NuclAT_20 - -
- (4780714) 4780714..4780779 + 66 NuclAT_20 - -
- (4780714) 4780714..4780779 + 66 NuclAT_21 - -
- (4780714) 4780714..4780779 + 66 NuclAT_21 - -
- (4780714) 4780714..4780779 + 66 NuclAT_21 - -
- (4780714) 4780714..4780779 + 66 NuclAT_21 - -
- (4780714) 4780714..4780779 + 66 NuclAT_22 - -
- (4780714) 4780714..4780779 + 66 NuclAT_22 - -
- (4780714) 4780714..4780779 + 66 NuclAT_22 - -
- (4780714) 4780714..4780779 + 66 NuclAT_22 - -
- (4780714) 4780714..4780779 + 66 NuclAT_24 - -
- (4780714) 4780714..4780779 + 66 NuclAT_24 - -
- (4780714) 4780714..4780779 + 66 NuclAT_24 - -
- (4780714) 4780714..4780779 + 66 NuclAT_24 - -
- (4780714) 4780714..4780779 + 66 NuclAT_25 - -
- (4780714) 4780714..4780779 + 66 NuclAT_25 - -
- (4780714) 4780714..4780779 + 66 NuclAT_25 - -
- (4780714) 4780714..4780779 + 66 NuclAT_25 - -
MW398_RS24290 (4781069) 4781069..4782169 - 1101 WP_000063608.1 sodium-potassium/proton antiporter ChaA -
MW398_RS24295 (4782439) 4782439..4782669 + 231 WP_001146444.1 putative cation transport regulator ChaB -
MW398_RS24300 (4782827) 4782827..4783522 + 696 WP_024187950.1 glutathione-specific gamma-glutamylcyclotransferase -
MW398_RS24305 (4783566) 4783566..4783919 - 354 WP_001169659.1 DsrE/F sulfur relay family protein YchN -
MW398_RS24310 (4784104) 4784104..4785498 + 1395 WP_000086188.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3971.74 Da        Isoelectric Point: 11.4779

>T242090 WP_000170963.1 NZ_CP095505:c4780664-4780557 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

>T242090 NZ_OV753634:c2712610-2711288 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGCGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGAGGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATCACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGAGCGGATCGTCAGGCGCTATCAG
GCGCGTTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGGCGGGACAGCGTAGGGGCGGTGACGCTGCTGCCGCCGGG
GGAAGAGGCGCATCTTGCCGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAGCTGACCGCTTTGCTGACCGCCTACCAGT
CGGATATTCCTCTCGGAATGGTGACCGGCCAGGACGATTTTCGTATCTCGGTGGCCGGCGCTCAGGAGAAAACCGCGCTG
CTGCGAATGGGCGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCTATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATTTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCAACACGCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCATTCGGCATACCGTCGTCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGTTCCAGTGAGGCCCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGCGGCAGCTACCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCGGTGCTGGGCGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACGGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTCCCCCGGGAGCAGATGCTGGCGATCCTGGGCGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCGGACGCTGCCGTCGGACTTTTCCGCCCACGTCTGGCGGGCCATCACGGAGAACATGCT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGGGATAG

Antitoxin


Download         Length: 67 bp

>AT242090 NZ_CP095505:4780712-4780778 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References