Detailed information of TA system TA241397

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2017488..2017704
• Replicon: chromosome
• Accession: NZ_CP095119
• Organism: Staphylococcus aureus strain IVB6154

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: MUA68_RS10220
• Protein ID: WP_000255428.1
• Coordinates: 2017597..2017704 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2017488..2017542 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA68_RS10190	2012604..2013413	-	810	WP_000830380.1	monofunctional peptidoglycan glycosyltransferase SgtB	-
MUA68_RS10195	2013754..2014269	-	516	WP_262520276.1	type 1 glutamine amidotransferase domain-containing protein	-
MUA68_RS10200	2014399..2014560	-	162	WP_001005407.1	SE1561 family protein	-
MUA68_RS10205	2015697..2016188	-	492	WP_252559491.1	staphylokinase	-
MUA68_RS10210	2016378..2017133	-	756	WP_000861038.1	CHAP domain-containing protein	-
MUA68_RS10215	2017145..2017399	-	255	WP_000611513.1	phage holin	-
-	2017488..2017542	+	55	-	-	Antitoxin
MUA68_RS10220	2017597..2017704	-	108	WP_000255428.1	putative holin-like toxin	Toxin
MUA68_RS10225	2017904..2018200	-	297	WP_000539688.1	DUF2951 domain-containing protein	-
MUA68_RS10230	2018258..2018545	-	288	WP_001040260.1	hypothetical protein	-
MUA68_RS10235	2018592..2018744	-	153	WP_001153680.1	hypothetical protein	-
MUA68_RS10240	2018734..2022519	-	3786	WP_262520278.1	phage tail spike protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3830.78 Da
• Isoelectric Point: 10.4997

>T241397 WP_000255428.1 NZ_CP095119:c2017704-2017597 [Staphylococcus aureus]
VVSVVDALNLMFSFGMFIVTLLGLVIAIVKLNHKK

Nucleotide

• Length: 108 bp

>T241397 NZ_LT992462:c728579-728403 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 55 bp

>AT241397 NZ_CP095119:2017488-2017542 [Staphylococcus aureus]
AAAAAGGCAACATGCGTAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin