Detailed information of TA system TA241392

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1928639..1928819
• Replicon: chromosome
• Accession: NZ_CP095119
• Organism: Staphylococcus aureus strain IVB6154

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MUA68_RS09625
• Protein ID: WP_001801861.1
• Coordinates: 1928639..1928734 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1928762..1928819 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA68_RS09580	1924022..1925017	+	996	WP_262520204.1	DUF4352 domain-containing protein	-
MUA68_RS09585	1925093..1925719	+	627	WP_262520205.1	hypothetical protein	-
MUA68_RS09590	1925760..1926107	+	348	WP_262520207.1	DUF3969 family protein	-
MUA68_RS09595	1926180..1926752	+	573	Protein_1893	hypothetical protein	-
MUA68_RS09600	1927082..1927267	-	186	WP_262522093.1	hypothetical protein	-
MUA68_RS09605	1927269..1927445	-	177	WP_154285032.1	hypothetical protein	-
MUA68_RS09610	1927456..1927781	-	326	Protein_1896	hypothetical protein	-
MUA68_RS09615	1927808..1928113	-	306	WP_233682504.1	IS3 family transposase	-
MUA68_RS09620	1928155..1928391	-	237	WP_262520211.1	hypothetical protein	-
MUA68_RS09625	1928639..1928734	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1928762..1928819	-	58	-	-	Antitoxin
MUA68_RS09630	1928857..1928958	+	102	WP_262520213.1	hypothetical protein	-
MUA68_RS09635	1928936..1929112	-	177	Protein_1901	transposase	-
MUA68_RS09640	1929280..1929723	-	444	WP_262520214.1	DUF1433 domain-containing protein	-
MUA68_RS09645	1929723..1930166	-	444	WP_262520215.1	DUF1433 domain-containing protein	-
MUA68_RS09650	1930166..1930609	-	444	Protein_1904	DUF1433 domain-containing protein	-
MUA68_RS09655	1931137..1933557	+	2421	WP_262520216.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1928155..1928391	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T241392 WP_001801861.1 NZ_CP095119:1928639-1928734 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T241392 NZ_LT992461:c1862327-1862139 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT241392 NZ_CP095119:c1928819-1928762 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACCATTTGCGGTAGTGAGGGG

Structures

Antitoxin