Detailed information of TA system TA241389

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF1/-
• Location: 950271..950609
• Replicon: chromosome
• Accession: NZ_CP095119
• Organism: Staphylococcus aureus strain IVB6154

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: MUA68_RS04915
• Protein ID: WP_262522028.1
• Coordinates: 950271..950447 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	950435..950609 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA68_RS04895	948056..948208	+	153	WP_001153680.1	hypothetical protein	-
MUA68_RS04900	948255..948542	+	288	WP_001040259.1	hypothetical protein	-
MUA68_RS04905	948598..948972	+	375	WP_262521123.1	hypothetical protein	-
MUA68_RS04910	949389..950162	+	774	WP_262521622.1	staphylococcal enterotoxin type A	-
MUA68_RS04915	950271..950447	+	177	WP_262522028.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	950435..950609	-	175	-	-	Antitoxin
MUA68_RS04925	950659..950913	+	255	WP_000611513.1	phage holin	-
MUA68_RS04930	950925..951680	+	756	WP_262521624.1	CHAP domain-containing protein	-
MUA68_RS04935	952018..952944	+	927	WP_262521625.1	bi-component leukocidin LukMF' subunit M	-
MUA68_RS04940	952946..953914	+	969	WP_262521627.1	bi-component leukocidin LukMF' subunit F'	-
MUA68_RS04945	954433..955020	+	588	WP_000448196.1	hypothetical protein	-
MUA68_RS04950	955017..955472	+	456	WP_000971220.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6869.39 Da
• Isoelectric Point: 10.4654

>T241389 WP_262522028.1 NZ_CP095119:950271-950447 [Staphylococcus aureus]
MDRWWLSEYNEVVPMVALLKSLERRRLMITISTMLQFGLFLIAFIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

>T241389 NZ_LT992461:c349612-349508 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 175 bp

>AT241389 NZ_CP095119:c950609-950435 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Structures

Antitoxin