Detailed information of TA system TA241366

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1034647..1034827
• Replicon: chromosome
• Accession: NZ_CP095116
• Organism: Staphylococcus aureus strain IVB6156

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MUA78_RS05310
• Protein ID: WP_001801861.1
• Coordinates: 1034732..1034827 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1034647..1034704 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA78_RS05295	1029734..1033845	+	4112	Protein_1000	SMEK domain-containing protein	-
MUA78_RS05300	1034354..1034470	+	117	Protein_1001	transposase	-
MUA78_RS05305	1034508..1034609	-	102	WP_001791232.1	hypothetical protein	-
-	1034647..1034704	+	58	-	-	Antitoxin
MUA78_RS05310	1034732..1034827	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
MUA78_RS05315	1035279..1035725	+	447	WP_000747809.1	DUF1433 domain-containing protein	-
MUA78_RS05320	1036412..1036795	+	384	WP_000070811.1	hypothetical protein	-
MUA78_RS05325	1036806..1036982	+	177	WP_000375476.1	hypothetical protein	-
MUA78_RS05330	1036984..1037169	+	186	WP_000809858.1	hypothetical protein	-
MUA78_RS05335	1037976..1038812	-	837	WP_000190484.1	ATP-binding cassette domain-containing protein	-
MUA78_RS05340	1039188..1039760	-	573	WP_000414229.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF2829 (2-69)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T241366 WP_001801861.1 NZ_CP095116:c1034827-1034732 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T241366 NZ_LT992458:c239932-239687 [Staphylococcus aureus]
ATGAACATTCAAGAAGCAACTAAGATAGCTACAAAAAATCTTGTCTCTATGACACGGAAAGATTGGAAAGAAAGTCATCG
AACTAAGATATTACCAACAAATGATAGTTTTTTACAATGCATCATTTCAAATAGCGATGGGACAAACCTTATCAGATATT
GGCAACCTTCAGCCGATGACCTCATGGCAAATGATTGGGAAGTTATAAACCCAACTAGAGACCAGGAATTATTGAAGCAA
TTTTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT241366 NZ_CP095116:1034647-1034704 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin