Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1949618..1949798 Replicon chromosome
Accession NZ_CP095112
Organism Staphylococcus aureus strain IVB6157

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MUA55_RS09520 Protein ID WP_001801861.1
Coordinates 1949618..1949713 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1949741..1949798 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA55_RS09495 (MUA55_09500) 1944666..1946033 - 1368 WP_001093574.1 FRG domain-containing protein -
MUA55_RS09500 (MUA55_09505) 1946033..1946464 - 432 WP_262518258.1 ImmA/IrrE family metallo-endopeptidase -
MUA55_RS09505 (MUA55_09510) 1946457..1948103 - 1647 WP_000277741.1 IS1182-like element ISSau3 family transposase -
MUA55_RS09510 (MUA55_09515) 1948346..1948528 - 183 WP_262518259.1 hypothetical protein -
MUA55_RS09515 (MUA55_09520) 1948721..1949167 - 447 WP_000747804.1 DUF1433 domain-containing protein -
MUA55_RS09520 (MUA55_09525) 1949618..1949713 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1949741..1949798 - 58 - - Antitoxin
MUA55_RS09525 (MUA55_09530) 1949836..1949937 + 102 WP_001791232.1 hypothetical protein -
MUA55_RS09530 (MUA55_09535) 1950112..1950555 - 444 WP_001037039.1 DUF1433 domain-containing protein -
MUA55_RS09535 (MUA55_09540) 1950555..1950998 - 444 WP_000731421.1 DUF1433 domain-containing protein -
MUA55_RS09540 (MUA55_09545) 1950998..1951440 - 443 Protein_1878 DUF1433 domain-containing protein -
MUA55_RS09545 (MUA55_09550) 1951965..1954385 + 2421 WP_252559462.1 polysaccharide lyase 8 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1946457..1948103 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T241350 WP_001801861.1 NZ_CP095112:1949618-1949713 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T241350 NZ_LT992436:c890172-890020 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACTGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATTTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGAGAGTCAGTAA

Antitoxin


Download         Length: 58 bp

>AT241350 NZ_CP095112:c1949798-1949741 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References