Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2595842..2596026 Replicon chromosome
Accession NZ_CP094853
Organism Staphylococcus aureus strain NY2010

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag MTX62_RS13150 Protein ID WP_000482650.1
Coordinates 2595919..2596026 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2595842..2595902 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX62_RS13135 2591372..2591539 - 168 WP_001790576.1 hypothetical protein -
MTX62_RS13140 2591770..2593503 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
MTX62_RS13145 2593528..2595291 - 1764 WP_001064838.1 ABC transporter ATP-binding protein -
- 2595842..2595902 + 61 - - Antitoxin
MTX62_RS13150 2595919..2596026 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
MTX62_RS13155 2596160..2596546 - 387 WP_000779358.1 flippase GtxA -
MTX62_RS13160 2596814..2597956 + 1143 WP_001176863.1 glycerate kinase -
MTX62_RS13165 2598016..2598675 + 660 WP_000831298.1 membrane protein -
MTX62_RS13170 2598857..2600068 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
MTX62_RS13175 2600191..2600664 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T240672 WP_000482650.1 NZ_CP094853:c2596026-2595919 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T240672 NZ_LT615218:c2477178-2476912 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCAGCGAAATCAGATTTAAGGAAAATAAAACATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTATTGAGACTTTAAAAAATGATCCGTATAAAATAACACAATCTTTTGAAAAATTAGAGCCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTCGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 61 bp

>AT240672 NZ_CP094853:2595842-2595902 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References