Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2301674..2301891 Replicon chromosome
Accession NZ_CP094853
Organism Staphylococcus aureus strain NY2010

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag MTX62_RS11610 Protein ID WP_001802298.1
Coordinates 2301787..2301891 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2301674..2301729 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX62_RS11585 2297811..2298476 - 666 WP_001024094.1 SDR family oxidoreductase -
MTX62_RS11590 2298628..2298948 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
MTX62_RS11595 2298950..2299930 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
MTX62_RS11600 2300196..2301287 + 1092 WP_000495671.1 lytic regulatory protein -
- 2301674..2301729 + 56 - - Antitoxin
MTX62_RS11610 2301787..2301891 - 105 WP_001802298.1 hypothetical protein Toxin
MTX62_RS11615 2302052..2302535 - 484 Protein_2258 recombinase family protein -
MTX62_RS11620 2302578..2303714 - 1137 WP_000115564.1 SAP domain-containing protein -
MTX62_RS11625 2304003..2304095 + 93 WP_031872195.1 hypothetical protein -
MTX62_RS11635 2304800..2305657 - 858 WP_000370924.1 HAD family hydrolase -
MTX62_RS11640 2305725..2306507 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T240670 WP_001802298.1 NZ_CP094853:c2301891-2301787 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T240670 NZ_LT615218:c2164451-2164347 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT240670 NZ_CP094853:2301674-2301729 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References