Detailed information of TA system TA240656

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1905265..1905447
• Replicon: chromosome
• Accession: NZ_CP094853
• Organism: Staphylococcus aureus strain NY2010

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MTX62_RS09230
• Protein ID: WP_001801861.1
• Coordinates: 1905265..1905360 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1905388..1905447 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MTX62_RS09190	1900925..1901551	+	627	WP_000669046.1	hypothetical protein	-
MTX62_RS09195	1901592..1901936	+	345	WP_000627551.1	DUF3969 family protein	-
MTX62_RS09200	1902034..1902585	+	552	WP_000414205.1	hypothetical protein	-
MTX62_RS09205	1902803..1903444	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
MTX62_RS09210	1903558..1903743	-	186	WP_000809857.1	hypothetical protein	-
MTX62_RS09215	1903745..1903921	-	177	WP_000375476.1	hypothetical protein	-
MTX62_RS09220	1903932..1904315	-	384	WP_000070811.1	hypothetical protein	-
MTX62_RS09225	1904919..1905062	-	144	WP_001549059.1	transposase	-
MTX62_RS09230	1905265..1905360	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1905388..1905447	-	60	-	-	Antitoxin
MTX62_RS09235	1905483..1905584	+	102	WP_001791893.1	hypothetical protein	-
MTX62_RS09240	1905562..1905738	-	177	Protein_1824	transposase	-
MTX62_RS09245	1905932..1906309	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T240656 WP_001801861.1 NZ_CP094853:1905265-1905360 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T240656 NZ_LT606950:216035-216301 [Polynucleobacter necessarius]
GTGGTAGTTTGGGATTTGGTTTATTCCAAATATGCCTTAAAAGACGCTAAAAAAATTTCGGCTGCAGGCTTGAAAGATAG
GGCTCAGGCATTGCTCTCTATTTTAGAGATTGATCCATTTCGAATTCCGCCGCCGTATGAGAAATTGGTTGGTGATCTGA
AGGGGGCATACTCTCGCAGGATTAATATTCAACACCGCCTTGTCTATGAAGTATTTCGAAAAGAGAAAACGGTGCGCATC
TTGAGAATGTGGATGCACTACGAATGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT240656 NZ_CP094853:c1905447-1905388 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin