Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 98142..98655 Replicon chromosome
Accession NZ_CP094815
Organism Mammaliicoccus sciuri strain IVB6255

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MUA36_RS00465 Protein ID WP_243547843.1
Coordinates 98389..98655 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MUA36_RS00460 Protein ID WP_243523231.1
Coordinates 98142..98396 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA36_RS00445 (MUA36_00445) 93806..95044 - 1239 WP_262637245.1 MFS transporter -
MUA36_RS00450 (MUA36_00450) 95068..96138 - 1071 WP_243526228.1 alcohol dehydrogenase catalytic domain-containing protein -
MUA36_RS00455 (MUA36_00455) 96300..97931 + 1632 WP_262637246.1 ribulokinase -
MUA36_RS00460 (MUA36_00460) 98142..98396 + 255 WP_243523231.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MUA36_RS00465 (MUA36_00465) 98389..98655 + 267 WP_243547843.1 Txe/YoeB family addiction module toxin Toxin
MUA36_RS00470 (MUA36_00470) 98689..99570 - 882 WP_262637248.1 ABC transporter permease subunit -
MUA36_RS00475 (MUA36_00475) 99567..100421 - 855 WP_239705682.1 hypothetical protein -
MUA36_RS00480 (MUA36_00480) 100590..101063 - 474 WP_262637249.1 GNAT family N-acetyltransferase -
MUA36_RS00485 (MUA36_00485) 101213..101572 - 360 WP_262637250.1 hypothetical protein -
MUA36_RS00490 (MUA36_00490) 101730..102632 - 903 WP_262637251.1 hypothetical protein -
MUA36_RS00495 (MUA36_00495) 102872..103294 - 423 WP_049320184.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10450.95 Da        Isoelectric Point: 9.3660

>T240594 WP_243547843.1 NZ_CP094815:98389-98655 [Mammaliicoccus sciuri]
MSKRNITFTPSASEDYEYWLEQDKKLLKKINSLIKSIQRDSQLEGEGKPEPLKGNLQGYCSRRINHEHRLVYTVKENHII
IIGCRYHY

Download         Length: 267 bp

>T240594 NZ_LT596221:3455333-3455536 [Yersinia pseudotuberculosis]
ATGACAAAAACTGACTACCTGATGCGTTTAAGAAAATGTACGACTATCGATACGCTAGAACGTGTAATTGAAAAAAATAA
GTACGAACTTTCTGATGATGAACTGGAATTGTTTTACTCAGCTGCAGACCATCGCCTGGCTGAACTAACGATGAATAAGC
TTTATGATAAAATTCCACCTACTGTATGGCAACATGTGAAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9558.55 Da        Isoelectric Point: 4.2213

>AT240594 WP_243523231.1 NZ_CP094815:98142-98396 [Mammaliicoccus sciuri]
MTVISYSNARKNFRKLIDKVNNDSDIVTITTNESNAVLMGEDDYNSIMETLYLQQSPANAKHLAKSIEEAERNNTVEIDI
ESYE

Download         Length: 255 bp

>AT240594 NZ_LT596221:3454916-3455284 [Yersinia pseudotuberculosis]
ATGGATGAGTACTCGCCTAAGCGGCATGACATTGCCCAACTGAAGTTTCTATGTGAAAGCTTGTATGATGAAGGTATTGC
AACTCTTGGCGACAGCCATCATGGCTGGATAAATGACCCAACGTCGGCCATAAACCTTCAACTCAATGATTTGATCGAGC
ATATAGCTTCATTTGTGATGAGTTTTAAAATAAAATACCCGGATGGAAGCCAGCTTTCCGAGTTAGTGGAAGAATATTTA
GACGACACATATACTCTGTTTAGTAGTTATGGAATCAATGATCCTGAATTGCGTCGCTGGCAGAAAACCAAAGAGCATTT
ATTCAGACTTTTCTCAGGGGAATACGTATGTACCCTGATGAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References