Detailed information of TA system TA240589

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 337923..338082
• Replicon: chromosome
• Accession: NZ_CP094814
• Organism: Staphylococcus agnetis strain IVB6175

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: MUA52_RS01465
• Protein ID: WP_107365594.1
• Coordinates: 337923..338024 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	338049..338082 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA52_RS01445 (MUA52_01445)	333476..333916	+	441	WP_262618705.1	antibiotic biosynthesis monooxygenase family protein	-
MUA52_RS01450 (MUA52_01450)	334428..335894	-	1467	WP_262618706.1	HAMP domain-containing sensor histidine kinase	-
MUA52_RS01455 (MUA52_01455)	335887..336564	-	678	WP_037565806.1	response regulator transcription factor	-
MUA52_RS01460 (MUA52_01460)	336778..337788	+	1011	WP_262618708.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
MUA52_RS01465 (MUA52_01465)	337923..338024	+	102	WP_107365594.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	338049..338082	-	34	-	-	Antitoxin
MUA52_RS01470 (MUA52_01470)	338182..338454	-	273	WP_262618709.1	DUF2316 family protein	-
MUA52_RS01475 (MUA52_01475)	338714..339124	+	411	WP_262618710.1	hypothetical protein	-
MUA52_RS01480 (MUA52_01480)	339242..339856	+	615	WP_105995353.1	DedA family protein	-
MUA52_RS01485 (MUA52_01485)	339929..340579	-	651	WP_262618711.1	zinc ribbon domain-containing protein	-
MUA52_RS01490 (MUA52_01490)	340798..342237	+	1440	WP_262618713.1	alkaline phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3789.56 Da
• Isoelectric Point: 10.7732

>T240589 WP_107365594.1 NZ_CP094814:337923-338024 [Staphylococcus agnetis]
MLDILVHITTTIISGCIVTLFAHWLRTRGNKHK

Nucleotide

• Length: 102 bp

>T240589 NZ_LT594504:c4545624-4545097 [Escherichia coli]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT240589 NZ_CP094814:c338082-338049 [Staphylococcus agnetis]
CACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin