Detailed information of TA system TA240584

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 338628..338787
• Replicon: chromosome
• Accession: NZ_CP094813
• Organism: Staphylococcus agnetis strain IVB6177

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: MUA84_RS01465
• Protein ID: WP_107365594.1
• Coordinates: 338628..338729 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	338754..338787 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA84_RS01445 (MUA84_01445)	334181..334621	+	441	WP_262618705.1	antibiotic biosynthesis monooxygenase family protein	-
MUA84_RS01450 (MUA84_01450)	335133..336599	-	1467	WP_262618706.1	HAMP domain-containing sensor histidine kinase	-
MUA84_RS01455 (MUA84_01455)	336592..337269	-	678	WP_037565806.1	response regulator transcription factor	-
MUA84_RS01460 (MUA84_01460)	337483..338493	+	1011	WP_262618708.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
MUA84_RS01465 (MUA84_01465)	338628..338729	+	102	WP_107365594.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	338754..338787	-	34	-	-	Antitoxin
MUA84_RS01470 (MUA84_01470)	338887..339159	-	273	WP_262618709.1	DUF2316 family protein	-
MUA84_RS01475 (MUA84_01475)	339419..339829	+	411	WP_262618710.1	hypothetical protein	-
MUA84_RS01480 (MUA84_01480)	339947..340561	+	615	WP_105995353.1	DedA family protein	-
MUA84_RS01485 (MUA84_01485)	340634..341284	-	651	WP_262618711.1	zinc ribbon domain-containing protein	-
MUA84_RS01490 (MUA84_01490)	341503..342942	+	1440	WP_262618713.1	alkaline phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3789.56 Da
• Isoelectric Point: 10.7732

>T240584 WP_107365594.1 NZ_CP094813:338628-338729 [Staphylococcus agnetis]
MLDILVHITTTIISGCIVTLFAHWLRTRGNKHK

Nucleotide

• Length: 102 bp

>T240584 NZ_LT594504:c3786679-3786344 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 34 bp

>AT240584 NZ_CP094813:c338787-338754 [Staphylococcus agnetis]
CACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin