Detailed information of TA system TA240567

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 336255..336414
• Replicon: chromosome
• Accession: NZ_CP094809
• Organism: Staphylococcus agnetis strain IVB6197

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: MUA95_RS01480
• Protein ID: WP_107365594.1
• Coordinates: 336255..336356 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	336381..336414 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA95_RS01460 (MUA95_01460)	331808..332248	+	441	WP_262626543.1	antibiotic biosynthesis monooxygenase family protein	-
MUA95_RS01465 (MUA95_01465)	332760..334226	-	1467	WP_262618706.1	HAMP domain-containing sensor histidine kinase	-
MUA95_RS01470 (MUA95_01470)	334219..334896	-	678	WP_262626544.1	response regulator transcription factor	-
MUA95_RS01475 (MUA95_01475)	335110..336120	+	1011	WP_262626545.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
MUA95_RS01480 (MUA95_01480)	336255..336356	+	102	WP_107365594.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	336381..336414	-	34	-	-	Antitoxin
MUA95_RS01485 (MUA95_01485)	336514..336786	-	273	WP_262618709.1	DUF2316 family protein	-
MUA95_RS01490 (MUA95_01490)	337046..337456	+	411	WP_262618710.1	hypothetical protein	-
MUA95_RS01495 (MUA95_01495)	337574..338188	+	615	WP_105995353.1	DedA family protein	-
MUA95_RS01500 (MUA95_01500)	338261..338911	-	651	WP_262618711.1	zinc ribbon domain-containing protein	-
MUA95_RS01505 (MUA95_01505)	339130..340569	+	1440	WP_262626546.1	alkaline phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3789.56 Da
• Isoelectric Point: 10.7732

>T240567 WP_107365594.1 NZ_CP094809:336255-336356 [Staphylococcus agnetis]
MLDILVHITTTIISGCIVTLFAHWLRTRGNKHK

Nucleotide

• Length: 102 bp

>T240567 NZ_LT592162:2355-2633 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin

Nucleotide

• Length: 34 bp

>AT240567 NZ_CP094809:c336414-336381 [Staphylococcus agnetis]
CACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin