Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2503492..2503676 Replicon chromosome
Accession NZ_CP094800
Organism Staphylococcus aureus strain IVB6158

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag MUA38_RS12515 Protein ID WP_000482647.1
Coordinates 2503569..2503676 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2503492..2503552 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA38_RS12500 2498946..2499113 - 168 WP_031901225.1 hypothetical protein -
MUA38_RS12505 2499344..2501077 - 1734 Protein_2418 ABC transporter ATP-binding protein/permease -
MUA38_RS12510 2501102..2502865 - 1764 WP_250425583.1 ABC transporter ATP-binding protein -
- 2503492..2503552 + 61 - - Antitoxin
MUA38_RS12515 2503569..2503676 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
MUA38_RS12520 2503810..2504196 - 387 WP_000779350.1 flippase GtxA -
MUA38_RS12525 2504464..2505606 + 1143 WP_001176867.1 glycerate kinase -
MUA38_RS12530 2505666..2506325 + 660 WP_000831298.1 membrane protein -
MUA38_RS12535 2506508..2507719 + 1212 WP_250425584.1 multidrug effflux MFS transporter -
MUA38_RS12540 2507842..2508315 - 474 WP_000456488.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T240537 WP_000482647.1 NZ_CP094800:c2503676-2503569 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T240537 NZ_LT591903:2355-2633 [Neisseria gonorrhoeae]
ATGTACGCGATTTCTTTTGATTTGGTGGTTGCCGATACCGCTCAAAACCATCCGAAAGGCATTTCCCAAGCCTACGCGGA
TATTGGATACACCCTGCGGAAATTCGGCTTTACCCGCATTCAGGGAAGTTTGTACACCTGCCAAAACGAAGATATGGCTA
ACCTGTTTTCAGCCATCAACGAGCTAAAAGCTCTGCCTTGGTTTCCGTCTTCTGTCCGCGATATTCGGGCGTTCCGCATT
GAGCAGTGGTCTGATTTCACAAGTCTTGTGAAGTCTTAA

Antitoxin


Download         Length: 61 bp

>AT240537 NZ_CP094800:2503492-2503552 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References