Detailed information of TA system TA240510

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1901977..1902203
• Replicon: chromosome
• Accession: NZ_CP094799
• Organism: Staphylococcus aureus strain IVB6159

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA85_RS09120
• Protein ID: WP_057488488.1
• Coordinates: 1902099..1902203 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1901977..1902070 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA85_RS09070 (1897243)	1897243..1897443	-	201	WP_000498228.1	hypothetical protein	-
MUA85_RS09075 (1897457)	1897457..1897666	-	210	WP_262633435.1	hypothetical protein	-
MUA85_RS09080 (1898218)	1898218..1898940	-	723	WP_000504040.1	DUF3800 domain-containing protein	-
MUA85_RS09085 (1899283)	1899283..1899468	-	186	WP_001286805.1	hypothetical protein	-
MUA85_RS09090 (1899470)	1899470..1899580	-	111	WP_000139425.1	hypothetical protein	-
MUA85_RS09095 (1899651)	1899651..1899803	-	153	WP_001788502.1	hypothetical protein	-
MUA85_RS09100 (1900193)	1900193..1900684	-	492	WP_250406032.1	staphylokinase	-
MUA85_RS09105 (1900875)	1900875..1901630	-	756	WP_262633437.1	CHAP domain-containing protein	-
MUA85_RS09110 (1901642)	1901642..1901896	-	255	WP_000611512.1	phage holin	-
MUA85_RS09115 (1901948)	1901948..1902043	+	96	Protein_1793	hypothetical protein	-
- (1901977)	1901977..1902070	+	94	NuclAT_1	-	Antitoxin
- (1901977)	1901977..1902070	+	94	NuclAT_1	-	Antitoxin
- (1901977)	1901977..1902070	+	94	NuclAT_1	-	Antitoxin
- (1901977)	1901977..1902070	+	94	NuclAT_1	-	Antitoxin
MUA85_RS09120 (1902099)	1902099..1902203	-	105	WP_057488488.1	hypothetical protein	Toxin
MUA85_RS09125 (1902409)	1902409..1902708	-	300	WP_107240626.1	DUF2951 family protein	-
MUA85_RS09130 (1902747)	1902747..1902908	-	162	WP_250406035.1	hypothetical protein	-
MUA85_RS09135 (1902895)	1902895..1905081	-	2187	WP_262633440.1	phage tail protein	-
MUA85_RS09140 (1905097)	1905097..1906212	-	1116	WP_262633442.1	hypothetical protein	-
MUA85_RS09145 (1906229)	1906229..1907182	-	954	WP_250425907.1	phage tail family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / sak	1880171..1937880	57709

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3919.77 Da
• Isoelectric Point: 5.5724

>T240510 WP_057488488.1 NZ_CP094799:c1902203-1902099 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T240510 NZ_LT571449:c1604294-1604115 [Staphylococcus epidermidis]
ATGGCGAACAAAAAAGATTCCAAATTAAATTATCATGAAGAAGAAAATGCTATGGTTACCGACTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAGATTTCACAGGAAAATGATGAAGAAAAATTAAATCAATCTCATGATAACGAAGTTCGTT
CAGATTTAAAAAAACAGTAA

Antitoxin

Nucleotide

• Length: 94 bp

>AT240510 NZ_CP094799:1901977-1902070 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin