Detailed information of TA system TA240495

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2194708..2194924
• Replicon: chromosome
• Accession: NZ_CP094797
• Organism: Staphylococcus aureus strain IVB6163

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA16_RS10915
• Protein ID: WP_073392962.1
• Coordinates: 2194820..2194924 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2194708..2194763 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA16_RS10890	2190902..2191567	-	666	WP_001024099.1	SDR family oxidoreductase	-
MUA16_RS10895	2191719..2192039	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MUA16_RS10900	2192041..2193021	+	981	WP_262515911.1	CDF family zinc efflux transporter CzrB	-
MUA16_RS10905	2193287..2194378	+	1092	WP_262519352.1	transcriptional regulator	-
-	2194708..2194763	+	56	-	-	Antitoxin
MUA16_RS10915	2194820..2194924	-	105	WP_073392962.1	hypothetical protein	Toxin
MUA16_RS10920	2195604..2195762	+	159	WP_001792784.1	hypothetical protein	-
MUA16_RS10925	2196421..2197278	-	858	WP_000370937.1	HAD family hydrolase	-
MUA16_RS10930	2197346..2198128	-	783	WP_262515912.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T240495 WP_073392962.1 NZ_CP094797:c2194924-2194820 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T240495 NZ_LT556084:c4954720-4954343 [Citrobacter amalonaticus]
ATGCAAACCCAACCACTATCCTCAACTCAGGAGGCTACACCACGCCCGTCACCGGTGGAGATCTGGCAACGGCTTCTGAG
CCACCTGTTGGATCGTCACTACGGTCTGACACTCAACGACACTCCGTTCGGCAACGATGGCGTGATTCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGATCTGGTACGAACCGACCGTCGCGGTTTT
AACGCAGAAACACAGTCGCCTCTTCTCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGACTGATGACCCGAAA
CGATTACAGAACGGTGACCGACATCACCACCGGTAAATACCGGGAGGTGCAGCCATGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT240495 NZ_CP094797:2194708-2194763 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin