Detailed information of TA system TA240489

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1892744..1892924
• Replicon: chromosome
• Accession: NZ_CP094797
• Organism: Staphylococcus aureus strain IVB6163

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MUA16_RS09100
• Protein ID: WP_262519341.1
• Coordinates: 1892744..1892839 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1892867..1892924 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA16_RS09070	1887888..1888514	+	627	WP_000669038.1	hypothetical protein	-
MUA16_RS09075	1888555..1888899	+	345	WP_000627550.1	DUF3969 family protein	-
MUA16_RS09080	1888997..1889569	+	573	WP_000414222.1	hypothetical protein	-
MUA16_RS09085	1889718..1891085	-	1368	WP_001093574.1	FRG domain-containing protein	-
MUA16_RS09090	1891085..1891654	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
MUA16_RS09095	1891847..1892293	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
MUA16_RS09100	1892744..1892839	+	96	WP_262519341.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1892867..1892924	-	58	-	-	Antitoxin
MUA16_RS09105	1892962..1893063	+	102	WP_001791232.1	hypothetical protein	-
MUA16_RS09110	1893238..1893681	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
MUA16_RS09115	1893681..1894124	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
MUA16_RS09120	1894124..1894566	-	443	Protein_1794	DUF1433 domain-containing protein	-
MUA16_RS09125	1895091..1897511	+	2421	WP_262515765.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3582.37 Da
• Isoelectric Point: 10.4449

>T240489 WP_262519341.1 NZ_CP094797:1892744-1892839 [Staphylococcus aureus]
VMLIFVHIIVPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T240489 NZ_LT556084:2760552-2760655 [Citrobacter amalonaticus]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 58 bp

>AT240489 NZ_CP094797:c1892924-1892867 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin