Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 2474417..2474601 | Replicon | chromosome |
Accession | NZ_CP094793 | ||
Organism | Staphylococcus aureus strain IVB6165 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2P7CQJ7 |
Locus tag | MUA93_RS12275 | Protein ID | WP_000482647.1 |
Coordinates | 2474494..2474601 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 2474417..2474477 (+) |
Genomic Context
Location: 2474417..2474477 (61 bp)
Type: Antitoxin
Protein ID: -
Type: Antitoxin
Protein ID: -
Location: 2475389..2476531 (1143 bp)
Type: Others
Protein ID: WP_001176867.1
Type: Others
Protein ID: WP_001176867.1
Location: 2476591..2477250 (660 bp)
Type: Others
Protein ID: WP_000831298.1
Type: Others
Protein ID: WP_000831298.1
Location: 2477433..2478644 (1212 bp)
Type: Others
Protein ID: WP_001191927.1
Type: Others
Protein ID: WP_001191927.1
Location: 2469871..2470038 (168 bp)
Type: Others
Protein ID: WP_031927726.1
Type: Others
Protein ID: WP_031927726.1
Location: 2470269..2472002 (1734 bp)
Type: Others
Protein ID: WP_000486497.1
Type: Others
Protein ID: WP_000486497.1
Location: 2472027..2473790 (1764 bp)
Type: Others
Protein ID: WP_252549861.1
Type: Others
Protein ID: WP_252549861.1
Location: 2474494..2474601 (108 bp)
Type: Toxin
Protein ID: WP_000482647.1
Type: Toxin
Protein ID: WP_000482647.1
Location: 2474735..2475121 (387 bp)
Type: Others
Protein ID: WP_000779353.1
Type: Others
Protein ID: WP_000779353.1
Location: 2478767..2479240 (474 bp)
Type: Others
Protein ID: WP_000456493.1
Type: Others
Protein ID: WP_000456493.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MUA93_RS12260 (MUA93_12250) | 2469871..2470038 | - | 168 | WP_031927726.1 | hypothetical protein | - |
MUA93_RS12265 (MUA93_12255) | 2470269..2472002 | - | 1734 | WP_000486497.1 | ABC transporter ATP-binding protein | - |
MUA93_RS12270 (MUA93_12260) | 2472027..2473790 | - | 1764 | WP_252549861.1 | ABC transporter ATP-binding protein | - |
- | 2474417..2474477 | + | 61 | - | - | Antitoxin |
MUA93_RS12275 (MUA93_12265) | 2474494..2474601 | - | 108 | WP_000482647.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
MUA93_RS12280 (MUA93_12270) | 2474735..2475121 | - | 387 | WP_000779353.1 | flippase GtxA | - |
MUA93_RS12285 (MUA93_12275) | 2475389..2476531 | + | 1143 | WP_001176867.1 | glycerate kinase | - |
MUA93_RS12290 (MUA93_12280) | 2476591..2477250 | + | 660 | WP_000831298.1 | membrane protein | - |
MUA93_RS12295 (MUA93_12285) | 2477433..2478644 | + | 1212 | WP_001191927.1 | multidrug effflux MFS transporter | - |
MUA93_RS12300 (MUA93_12290) | 2478767..2479240 | - | 474 | WP_000456493.1 | GyrI-like domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4012.76 Da Isoelectric Point: 10.4935
>T240471 WP_000482647.1 NZ_CP094793:c2474601-2474494 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T240471 NZ_LT222313:c35220-34870 [Pseudomonas cerasi]
ATGAATACGTTTGCACTACGCTTTACCGAGGTTGCCCAGCAAAGCATTGAAGATCAGGTCGAGCACCTGGCTATCACTCA
GGGATTCTCATCAGCTGCTCAGCGCATAGATACCCTGATCGATGCCATCCAGGACAAGCTCCTGTCCACCCCTTTGGGCT
ACCCGGTCAGTCCACAGTTGAGTGAGCTGGGTGTACTGCACTATCGTGAGTTGAACACTGACGGATACCGGATCTTTTAT
GAGGTGATGGATTCTGATGGTATTACCGATATCGCCGTATTGCTCGTATTAGGCGGGAAACAAAGTGTGGAGCAGGCTCT
GATCCGCTACTGCCTGCTCCAGCCGATGTAG
ATGAATACGTTTGCACTACGCTTTACCGAGGTTGCCCAGCAAAGCATTGAAGATCAGGTCGAGCACCTGGCTATCACTCA
GGGATTCTCATCAGCTGCTCAGCGCATAGATACCCTGATCGATGCCATCCAGGACAAGCTCCTGTCCACCCCTTTGGGCT
ACCCGGTCAGTCCACAGTTGAGTGAGCTGGGTGTACTGCACTATCGTGAGTTGAACACTGACGGATACCGGATCTTTTAT
GAGGTGATGGATTCTGATGGTATTACCGATATCGCCGTATTGCTCGTATTAGGCGGGAAACAAAGTGTGGAGCAGGCTCT
GATCCGCTACTGCCTGCTCCAGCCGATGTAG
Antitoxin
Download Length: 61 bp
>AT240471 NZ_CP094793:2474417-2474477 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2P7CQJ7 |