Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2474417..2474601 Replicon chromosome
Accession NZ_CP094793
Organism Staphylococcus aureus strain IVB6165

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag MUA93_RS12275 Protein ID WP_000482647.1
Coordinates 2474494..2474601 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2474417..2474477 (+)

Genomic Context


--MUA93_RS12285MUA93_RS12290MUA93_RS12295MUA93_RS12260MUA93_RS12265MUA93_RS12270MUA93_RS12275MUA93_RS12280MUA93_RS12300
Location: 2474417..2474477 (61 bp)
Type: Antitoxin
Protein ID: -
Location: 2475389..2476531 (1143 bp)
Type: Others
Protein ID: WP_001176867.1
Location: 2476591..2477250 (660 bp)
Type: Others
Protein ID: WP_000831298.1
Location: 2477433..2478644 (1212 bp)
Type: Others
Protein ID: WP_001191927.1
Location: 2469871..2470038 (168 bp)
Type: Others
Protein ID: WP_031927726.1
Location: 2470269..2472002 (1734 bp)
Type: Others
Protein ID: WP_000486497.1
Location: 2472027..2473790 (1764 bp)
Type: Others
Protein ID: WP_252549861.1
Location: 2474494..2474601 (108 bp)
Type: Toxin
Protein ID: WP_000482647.1
Location: 2474735..2475121 (387 bp)
Type: Others
Protein ID: WP_000779353.1
Location: 2478767..2479240 (474 bp)
Type: Others
Protein ID: WP_000456493.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MUA93_RS12260 (MUA93_12250)2469871..2470038-168WP_031927726.1hypothetical protein-
MUA93_RS12265 (MUA93_12255)2470269..2472002-1734WP_000486497.1ABC transporter ATP-binding protein-
MUA93_RS12270 (MUA93_12260)2472027..2473790-1764WP_252549861.1ABC transporter ATP-binding protein-
-2474417..2474477+61--Antitoxin
MUA93_RS12275 (MUA93_12265)2474494..2474601-108WP_000482647.1type I toxin-antitoxin system Fst family toxinToxin
MUA93_RS12280 (MUA93_12270)2474735..2475121-387WP_000779353.1flippase GtxA-
MUA93_RS12285 (MUA93_12275)2475389..2476531+1143WP_001176867.1glycerate kinase-
MUA93_RS12290 (MUA93_12280)2476591..2477250+660WP_000831298.1membrane protein-
MUA93_RS12295 (MUA93_12285)2477433..2478644+1212WP_001191927.1multidrug effflux MFS transporter-
MUA93_RS12300 (MUA93_12290)2478767..2479240-474WP_000456493.1GyrI-like domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T240471 WP_000482647.1 NZ_CP094793:c2474601-2474494 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T240471 NZ_LT222313:c35220-34870 [Pseudomonas cerasi]
ATGAATACGTTTGCACTACGCTTTACCGAGGTTGCCCAGCAAAGCATTGAAGATCAGGTCGAGCACCTGGCTATCACTCA
GGGATTCTCATCAGCTGCTCAGCGCATAGATACCCTGATCGATGCCATCCAGGACAAGCTCCTGTCCACCCCTTTGGGCT
ACCCGGTCAGTCCACAGTTGAGTGAGCTGGGTGTACTGCACTATCGTGAGTTGAACACTGACGGATACCGGATCTTTTAT
GAGGTGATGGATTCTGATGGTATTACCGATATCGCCGTATTGCTCGTATTAGGCGGGAAACAAAGTGTGGAGCAGGCTCT
GATCCGCTACTGCCTGCTCCAGCCGATGTAG

Antitoxin


Download         Length: 61 bp

>AT240471 NZ_CP094793:2474417-2474477 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2P7CQJ7


Antitoxin

Download structure file

References