240458

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2601731..2601915 Replicon chromosome
Accession NZ_CP094791
Organism Staphylococcus aureus strain IVB6166

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag MUA80_RS13235 Protein ID WP_000482647.1
Coordinates 2601808..2601915 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2601731..2601791 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA80_RS13220 (MUA80_13195) 2597241..2597408 - 168 Protein_2562 hypothetical protein -
MUA80_RS13225 (MUA80_13200) 2597639..2599372 - 1734 WP_000486505.1 ABC transporter ATP-binding protein -
MUA80_RS13230 (MUA80_13205) 2599397..2601160 - 1764 WP_001064829.1 ABC transporter ATP-binding protein -
- 2601731..2601791 + 61 - - Antitoxin
MUA80_RS13235 (MUA80_13210) 2601808..2601915 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
MUA80_RS13240 (MUA80_13215) 2602049..2602435 - 387 WP_000779351.1 flippase GtxA -
MUA80_RS13245 (MUA80_13220) 2602703..2603845 + 1143 WP_001176855.1 glycerate kinase -
MUA80_RS13250 (MUA80_13225) 2603905..2604564 + 660 WP_000831298.1 membrane protein -
MUA80_RS13255 (MUA80_13230) 2604746..2605957 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
MUA80_RS13260 (MUA80_13235) 2606080..2606553 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T240458 WP_000482647.1 NZ_CP094791:c2601915-2601808 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T240458 NZ_LT009690:c2056941-2056765 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 61 bp

>AT240458 NZ_CP094791:2601731-2601791 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References