Detailed information of TA system TA240455

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2315030..2315308
• Replicon: chromosome
• Accession: NZ_CP094791
• Organism: Staphylococcus aureus strain IVB6166

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA80_RS11735
• Protein ID: WP_073392962.1
• Coordinates: 2315204..2315308 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2315030..2315208 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA80_RS11710 (MUA80_11685)	2310183..2310503	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MUA80_RS11715 (MUA80_11690)	2310505..2311485	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
MUA80_RS11720 (MUA80_11695)	2311751..2312842	+	1092	WP_000495684.1	hypothetical protein	-
MUA80_RS11725 (MUA80_11700)	2312872..2314518	-	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2315030..2315208	+	179	-	-	Antitoxin
MUA80_RS11735 (MUA80_11710)	2315204..2315308	-	105	WP_073392962.1	hypothetical protein	Toxin
MUA80_RS11740 (MUA80_11715)	2315988..2316146	+	159	WP_001792784.1	hypothetical protein	-
MUA80_RS11745 (MUA80_11720)	2316805..2317662	-	858	WP_000370937.1	HAD family hydrolase	-
MUA80_RS11750 (MUA80_11725)	2317730..2318512	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2312872..2314518	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T240455 WP_073392962.1 NZ_CP094791:c2315308-2315204 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T240455 NZ_LT009690:c884471-884007 [Staphylococcus aureus]
ATGGGATTATATGAAGAAACTTTAATACAACATGATTATATTGAAGTAAGAGAGGCTGATGTACTTCCAGATAATTTAGA
CGGGGTATGGTTAGGAGATTTAATTTTAATAAAGCGTGGTTTATCAGATAGAGAAAAGGCAGGAATTCTCTTCGAAGAAT
TAGCACATAATAAACTTACATACGGTGATATAGCTGATTACTCGAAATTCAACAATCGCAAGTTCGAAAATTACGCACGT
AGACACGGCTTTATCTCAGCAGTCCCGTTACGCGAAATTGTTGAAGCTTACAATTATGGCGTACGTAACTTGTATGAGTT
GTCTGAGTATCTACAATTAAGCGAAGAATACATATTAGAAGCAATAGAACAATATAAAAAGATATATGGTATTGGAACTC
ACTATGGCGAGTATTCTATTACATTTGAGCCGTTGAGAGTTTTTAAATTGCATCATATTGATTAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT240455 NZ_CP094791:2315030-2315208 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Antitoxin