Detailed information of TA system TA240437

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2315029..2315307
• Replicon: chromosome
• Accession: NZ_CP094789
• Organism: Staphylococcus aureus strain IVB6167

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA09_RS11730
• Protein ID: WP_073392962.1
• Coordinates: 2315203..2315307 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2315029..2315207 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA09_RS11705 (MUA09_11685)	2310182..2310502	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MUA09_RS11710 (MUA09_11690)	2310504..2311484	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
MUA09_RS11715 (MUA09_11695)	2311750..2312841	+	1092	WP_000495684.1	hypothetical protein	-
MUA09_RS11720 (MUA09_11700)	2312871..2314517	-	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2315029..2315207	+	179	-	-	Antitoxin
MUA09_RS11730 (MUA09_11710)	2315203..2315307	-	105	WP_073392962.1	hypothetical protein	Toxin
MUA09_RS11735 (MUA09_11715)	2315987..2316145	+	159	WP_001792784.1	hypothetical protein	-
MUA09_RS11740 (MUA09_11720)	2316804..2317661	-	858	WP_000370937.1	HAD family hydrolase	-
MUA09_RS11745 (MUA09_11725)	2317729..2318511	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2312871..2314517	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T240437 WP_073392962.1 NZ_CP094789:c2315307-2315203 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T240437 NZ_LS999560:3653356-3653574 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT240437 NZ_CP094789:2315029-2315207 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Antitoxin