Detailed information of TA system TA240409

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2315026..2315304
• Replicon: chromosome
• Accession: NZ_CP094785
• Organism: Staphylococcus aureus strain IVB6169

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA79_RS11710
• Protein ID: WP_073392962.1
• Coordinates: 2315200..2315304 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2315026..2315204 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA79_RS11685 (MUA79_11670)	2310179..2310499	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MUA79_RS11690 (MUA79_11675)	2310501..2311481	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
MUA79_RS11695 (MUA79_11680)	2311747..2312838	+	1092	WP_000495684.1	hypothetical protein	-
MUA79_RS11700 (MUA79_11685)	2312868..2314514	-	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2315026..2315204	+	179	-	-	Antitoxin
MUA79_RS11710 (MUA79_11695)	2315200..2315304	-	105	WP_073392962.1	hypothetical protein	Toxin
MUA79_RS11715 (MUA79_11700)	2315984..2316142	+	159	WP_001792784.1	hypothetical protein	-
MUA79_RS11720 (MUA79_11705)	2316801..2317658	-	858	WP_000370937.1	HAD family hydrolase	-
MUA79_RS11725 (MUA79_11710)	2317726..2318508	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2312868..2314514	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T240409 WP_073392962.1 NZ_CP094785:c2315304-2315200 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T240409 NZ_LS999206:684144-684431 [Enterobacter hormaechei]
ATGCCTATAGAGTATGAGTGGGATAGCAATAAGGCGAAAAGCAATCTGCAAAAACACGCCATTCGTTTTGAAGATGCAGT
TCTGGTTTTTGACGATCCCTGCCATTTGTCTGTTCAGGATCGTTATGAAAACGGGGAGTTTCGCTGGCAAACCATTGGTC
TTGTACAGGGCGTTATTGTCATTCTGGTCGCGCACACGGTACGTTTTGAAAGCGGGGATGAAATCATACGTATCATCAGT
GCGCGTAAAGCGGATCGTAAAGAGAGGAGGCGTTATGAGCATCGTTAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT240409 NZ_CP094785:2315026-2315204 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Antitoxin