Detailed information of TA system TA240384

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1516346..1516563
• Replicon: chromosome
• Accession: NZ_CP094783
• Organism: Staphylococcus aureus strain IVB6170

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: MUA30_RS07310
• Protein ID: WP_000253687.1
• Coordinates: 1516456..1516563 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1516346..1516401 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA30_RS07280	1511572..1512117	-	546	WP_001186912.1	ECF transporter S component	-
MUA30_RS07285	1512506..1513437	-	932	Protein_1428	DUF1672 domain-containing protein	-
MUA30_RS07290	1513528..1513743	-	216	WP_000126130.1	hypothetical protein	-
MUA30_RS07295	1514555..1515046	-	492	WP_252559491.1	staphylokinase	-
MUA30_RS07300	1515236..1515991	-	756	WP_045178739.1	CHAP domain-containing protein	-
MUA30_RS07305	1516003..1516257	-	255	WP_238522769.1	phage holin	-
-	1516346..1516401	+	56	-	-	Antitoxin
MUA30_RS07310	1516456..1516563	-	108	WP_000253687.1	putative holin-like toxin	Toxin
MUA30_RS07315	1516798..1517094	-	297	WP_000539688.1	DUF2951 domain-containing protein	-
MUA30_RS07320	1517152..1517439	-	288	WP_001040261.1	hypothetical protein	-
MUA30_RS07325	1517486..1517638	-	153	WP_001153681.1	hypothetical protein	-
MUA30_RS07330	1517628..1521413	-	3786	WP_262633917.1	phage tail spike protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sak / gnd	1513528..1578061	64533

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3844.80 Da
• Isoelectric Point: 10.4997

>T240384 WP_000253687.1 NZ_CP094783:c1516563-1516456 [Staphylococcus aureus]
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLNHKK

Nucleotide

• Length: 108 bp

>T240384 NZ_LS998785:1119552-1119863 [Escherichia coli]
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAGATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT240384 NZ_CP094783:1516346-1516401 [Staphylococcus aureus]
AAAAAGGGCAACATGCGTAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin