Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1966893..1967073 Replicon chromosome
Accession NZ_CP094778
Organism Staphylococcus aureus strain IVB6185

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MUA10_RS09625 Protein ID WP_001801861.1
Coordinates 1966893..1966988 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1967016..1967073 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA10_RS09595 (MUA10_09590) 1962037..1962663 + 627 WP_000669038.1 hypothetical protein -
MUA10_RS09600 (MUA10_09595) 1962704..1963048 + 345 WP_000627550.1 DUF3969 family protein -
MUA10_RS09605 (MUA10_09600) 1963146..1963718 + 573 WP_000414222.1 hypothetical protein -
MUA10_RS09610 (MUA10_09605) 1963867..1965234 - 1368 WP_262607390.1 FRG domain-containing protein -
MUA10_RS09615 (MUA10_09610) 1965234..1965803 - 570 WP_000125075.1 ImmA/IrrE family metallo-endopeptidase -
MUA10_RS09620 (MUA10_09615) 1965996..1966442 - 447 WP_000747804.1 DUF1433 domain-containing protein -
MUA10_RS09625 (MUA10_09620) 1966893..1966988 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1967016..1967073 - 58 - - Antitoxin
MUA10_RS09630 (MUA10_09625) 1967111..1967212 + 102 WP_001791232.1 hypothetical protein -
MUA10_RS09635 (MUA10_09630) 1967387..1967830 - 444 WP_001037039.1 DUF1433 domain-containing protein -
MUA10_RS09640 (MUA10_09635) 1967830..1968273 - 444 WP_000731421.1 DUF1433 domain-containing protein -
MUA10_RS09645 (MUA10_09640) 1968273..1968715 - 443 Protein_1896 DUF1433 domain-containing protein -
MUA10_RS09650 (MUA10_09645) 1969240..1971660 + 2421 WP_045179297.1 polysaccharide lyase 8 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T240344 WP_001801861.1 NZ_CP094778:1966893-1966988 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T240344 NZ_LS992192:c4776431-4776258 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTTTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 58 bp

>AT240344 NZ_CP094778:c1967073-1967016 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References