Detailed information of TA system TA240317

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1915629..1915855
• Replicon: chromosome
• Accession: NZ_CP094773
• Organism: Staphylococcus aureus strain IVB6195

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA47_RS09180
• Protein ID: WP_057488488.1
• Coordinates: 1915751..1915855 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1915629..1915722 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA47_RS09135 (1911818)	1911818..1912018	-	201	WP_000498228.1	hypothetical protein	-
MUA47_RS09140 (1912032)	1912032..1912241	-	210	WP_000187864.1	hypothetical protein	-
MUA47_RS09145 (1912935)	1912935..1913120	-	186	WP_001286805.1	hypothetical protein	-
MUA47_RS09150 (1913122)	1913122..1913232	-	111	WP_000139425.1	hypothetical protein	-
MUA47_RS09155 (1913303)	1913303..1913455	-	153	WP_001788502.1	hypothetical protein	-
MUA47_RS09160 (1913845)	1913845..1914336	-	492	WP_250406032.1	staphylokinase	-
MUA47_RS09165 (1914527)	1914527..1915282	-	756	WP_250406033.1	CHAP domain-containing protein	-
MUA47_RS09170 (1915294)	1915294..1915548	-	255	WP_000611512.1	phage holin	-
MUA47_RS09175 (1915600)	1915600..1915695	+	96	Protein_1805	hypothetical protein	-
- (1915629)	1915629..1915722	+	94	NuclAT_1	-	Antitoxin
- (1915629)	1915629..1915722	+	94	NuclAT_1	-	Antitoxin
- (1915629)	1915629..1915722	+	94	NuclAT_1	-	Antitoxin
- (1915629)	1915629..1915722	+	94	NuclAT_1	-	Antitoxin
MUA47_RS09180 (1915751)	1915751..1915855	-	105	WP_057488488.1	hypothetical protein	Toxin
MUA47_RS09185 (1916061)	1916061..1916360	-	300	WP_107240626.1	DUF2951 family protein	-
MUA47_RS09190 (1916399)	1916399..1916560	-	162	WP_250406035.1	hypothetical protein	-
MUA47_RS09195 (1916547)	1916547..1918733	-	2187	WP_250406036.1	phage tail protein	-
MUA47_RS09200 (1918749)	1918749..1919864	-	1116	WP_250406037.1	hypothetical protein	-
MUA47_RS09205 (1919881)	1919881..1920834	-	954	WP_250425907.1	phage tail family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / sak	1894746..1951295	56549

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3919.77 Da
• Isoelectric Point: 5.5724

>T240317 WP_057488488.1 NZ_CP094773:c1915855-1915751 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T240317 NZ_LS992190:c4914965-4914654 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGAACGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTCTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin

Nucleotide

• Length: 94 bp

>AT240317 NZ_CP094773:1915629-1915722 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin