Detailed information of TA system TA240315

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1887696..1887876
• Replicon: chromosome
• Accession: NZ_CP094773
• Organism: Staphylococcus aureus strain IVB6195

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MUA47_RS09030
• Protein ID: WP_001801861.1
• Coordinates: 1887696..1887791 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1887819..1887876 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA47_RS09000	1882763..1883335	+	573	WP_250426005.1	hypothetical protein	-
MUA47_RS09005	1883711..1884547	+	837	WP_000190484.1	ATP-binding cassette domain-containing protein	-
MUA47_RS09010	1885354..1885539	-	186	WP_000809858.1	hypothetical protein	-
MUA47_RS09015	1885541..1885717	-	177	WP_000375476.1	hypothetical protein	-
MUA47_RS09020	1885728..1886111	-	384	WP_000070811.1	hypothetical protein	-
MUA47_RS09025	1886798..1887244	-	447	WP_000747809.1	DUF1433 domain-containing protein	-
MUA47_RS09030	1887696..1887791	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1887819..1887876	-	58	-	-	Antitoxin
MUA47_RS09035	1887914..1888015	+	102	WP_001791232.1	hypothetical protein	-
MUA47_RS09040	1888053..1888169	-	117	Protein_1778	transposase	-
MUA47_RS09045	1888678..1892791	-	4114	Protein_1779	SMEK domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T240315 WP_001801861.1 NZ_CP094773:1887696-1887791 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T240315 NZ_LS992190:c4495714-4495364 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT240315 NZ_CP094773:c1887876-1887819 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin