Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2214282..2214498 Replicon chromosome
Accession NZ_CP094772
Organism Staphylococcus aureus strain IVB6196

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag MUA50_RS11095 Protein ID WP_073392962.1
Coordinates 2214394..2214498 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2214282..2214337 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA50_RS11070 2210476..2211141 - 666 WP_001024099.1 SDR family oxidoreductase -
MUA50_RS11075 2211293..2211613 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
MUA50_RS11080 2211615..2212595 + 981 WP_262515911.1 CDF family zinc efflux transporter CzrB -
MUA50_RS11085 2212861..2213952 + 1092 WP_000495684.1 hypothetical protein -
- 2214282..2214337 + 56 - - Antitoxin
MUA50_RS11095 2214394..2214498 - 105 WP_073392962.1 hypothetical protein Toxin
MUA50_RS11100 2215178..2215336 + 159 WP_001792784.1 hypothetical protein -
MUA50_RS11105 2215995..2216852 - 858 WP_000370937.1 HAD family hydrolase -
MUA50_RS11110 2216920..2217702 - 783 WP_262515912.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T240302 WP_073392962.1 NZ_CP094772:c2214498-2214394 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T240302 NZ_LS992190:1960235-1960486 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGACAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 56 bp

>AT240302 NZ_CP094772:2214282-2214337 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References