240273

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 944548..944728 Replicon chromosome
Accession NZ_CP094768
Organism Staphylococcus aureus strain IVB6202

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MUA94_RS04805 Protein ID WP_001801861.1
Coordinates 944633..944728 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 944548..944605 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA94_RS04790 (MUA94_04780) 939636..943747 + 4112 Protein_902 SMEK domain-containing protein -
MUA94_RS04795 (MUA94_04785) 944255..944371 + 117 Protein_903 transposase -
MUA94_RS04800 (MUA94_04790) 944409..944510 - 102 WP_001791232.1 hypothetical protein -
- 944548..944605 + 58 - - Antitoxin
MUA94_RS04805 (MUA94_04795) 944633..944728 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
MUA94_RS04810 (MUA94_04800) 945180..945626 + 447 WP_000747809.1 DUF1433 domain-containing protein -
MUA94_RS04815 (MUA94_04805) 946313..946696 + 384 WP_000070811.1 hypothetical protein -
MUA94_RS04820 (MUA94_04810) 946707..946883 + 177 WP_000375476.1 hypothetical protein -
MUA94_RS04825 (MUA94_04815) 946885..947070 + 186 WP_000809858.1 hypothetical protein -
MUA94_RS04830 (MUA94_04820) 947876..948709 - 834 WP_262538511.1 ATP-binding cassette domain-containing protein -
MUA94_RS04835 (MUA94_04825) 949085..949657 - 573 WP_000414222.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T240273 WP_001801861.1 NZ_CP094768:c944728-944633 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T240273 NZ_LS992185:c2877501-2877398 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 58 bp

>AT240273 NZ_CP094768:944548-944605 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References